Synthesis, spectroscopic studies, and preliminary antibacterial assays of a palladium(II) complex with 2-mercaptothiazoline

Autor(es)

Bergamini, F. R. G. ^[1] ; Abbehausen, C. ^[1] ; Magalhaes, A. ^[1] ; Lustri, W. R. ^[2] ; Gomes, A. F. ^[1] ; Gozzo, F. C. ^[1] ; Corbi, P. P. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Campinas UNICAMP, Inst Chem, BR-13083970 Campinas, SP - Brazil

^[2] Centro Univ Araraquara, Dept Biol & Hlth Sci, BR-14801320 Araraquara, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Coordination Chemistry; v. 64, n. 17, p. 3092-3101, 2011.
• Citações Web of Science: 10

Resumo

In this article, synthesis of a palladium(II) complex with 2-mercaptothiazoline in aqueous solution is presented. Composition of the complex was defined as 1 : 2 (metal : ligand). Infrared and solid-state nuclear magnetic resonance indicate ligand coordination to Pd(II) through nitrogen of thiazole ring and sulfur of thiol. ESI-QTOF-mass spectrometric analysis shows primarily the dimeric form in solution. An antibiogram assay of the complex was performed by the disc diffusion method. The compound did not show antibacterial activity against the considered bacterial cells in the tested concentrations. (AU)

• Processo FAPESP: 06/55367-2 - Complexos metálicos de platina (II), platina (IV), paládio (II), ouro (I) e ouro (III) com aminoácidos e derivados: síntese, caracterização e aplicações farmacológicas
• Beneficiário: Pedro Paulo Corbi
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 08/57805-2 - Instituto de Bioanalítica
• Beneficiário: Lauro Tatsuo Kubota
• Modalidade de apoio: Auxílio à Pesquisa - Temático