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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

SPERM QUALITY IN ADULT MALE RATS EXPOSED TO CADMIUM IN UTERO AND LACTATION

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Autor(es):
Banzato, Thais Petrochelli [1] ; Godinho, Antonio Francisco [2] ; Mathias da Silva Zacarin, Elaine Cristina [3] ; Perobelli, Juliana Elaine [4] ; Fernandez, Carla Dal Bianco [4] ; Alves Favareto, Ana Paula [4] ; Kempinas, Wilma De Grava [5]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] UNESP Univ Estadual Paulista, Grad Program Gen & Appl Biol, Inst Biosci, BR-18618970 Botucatu, SP - Brazil
[2] UNESP Univ Estadual Paulista, Ctr Toxicol Assistance CEATOX, Inst Biosci, BR-18618970 Botucatu, SP - Brazil
[3] Fed Univ Sao Carlos UFSCAR, Lab Struct & Funct Biol, Campus Sorocaba, SP - Brazil
[4] State Univ Campinas UNICAMP, Inst Biol, Grad Program Cellular & Struct Biol, Campinas, SP - Brazil
[5] UNESP Univ Estadual Paulista, Dept Morphol, Inst Biosci, BR-18618970 Botucatu, SP - Brazil
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES; v. 75, n. 16-17, SI, p. 1047-1058, 2012.
Citações Web of Science: 10
Resumo

Recent studies indicate that several anomalies of the male reproductive system may be produced by acute or chronic exposure to chemical substances released into the environment, attributed to increased industrial development. Among these substances are trace metals such as cadmium (Cd). The aim of this study was to assess reproductive parameters in adult male rats whose mothers were exposed to Cd during pregnancy and lactation. For this, pregnant rats were divided into two experimental groups: treated rats, which received ad libitum cadmium acetate (CdAc) solution in distilled water (10 mg Cd/L), and control rats, which received sodium acetate (NaAc) solution in distilled water (equimolar to the CdAc). The results showed that the exposure to Cd in utero and through lactation adversely affected sperm quality of adult rats, as evidenced by compromised sperm morphology and motility and increased rate of cell death in testis. (AU)

Processo FAPESP: 09/02044-0 - Avaliação de parâmetros reprodutivos de ratos machos, púberes e adultos, expostos ao cádmio in útero e durante a lactação
Beneficiário:Thais Petrochelli Banzato
Linha de fomento: Bolsas no Brasil - Iniciação Científica