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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Drinking of mate and the risk of cancers of the upper aerodigestive tract in Latin America: a case-control study

Texto completo
Autor(es):
Szymanska, K. [1] ; Matos, E. [2] ; Hung, R. J. [1, 3] ; Wuensch-Filho, V. [4] ; Eluf-Neto, J. [4] ; Menezes, A. [5] ; Daudt, A. W. [6] ; Brennan, P. [1] ; Boffetta, P. [7, 1, 8]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Int Agcy Res Canc, F-69372 Lyon - France
[2] Univ Buenos Aires, Buenos Aires, DF - Argentina
[3] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5 - Canada
[4] Univ Sao Paolo, Sao Paulo - Brazil
[5] Univ Fed Pelotas, Pelotas - Brazil
[6] Clin Hosp Porto Alegre, Porto Alegre, RS - Brazil
[7] Int Prevent Res Inst, Lyon - France
[8] Mt Sinai Sch Med, Tisch Canc Inst, New York, NY 10029 - USA
Número total de Afiliações: 8
Tipo de documento: Artigo Científico
Fonte: CANCER CAUSES & CONTROL; v. 21, n. 11, p. 1799-1806, NOV 2010.
Citações Web of Science: 16
Resumo

Cancers of the upper aerodigestive tract (UADT: oral cavity, oropharynx, hypopharynx, larynx, esophagus) have high incidence rates all over the world and they are especially frequent in some parts of Latin America. In this study, we have evaluated the role of the consumption of mat,, a hot herb-based beverage, based on 1168 UADT squamous-cell carcinoma cases and 1,026 frequency-matched controls enrolled from four centers in Brazil and Argentina. The effect of mat, drinking on the risk of head-and-neck cancers was borderline significant. A significant effect was observed only for cancer of the esophagus (OR 3.81 (95% CI 1.75-8.30)). While duration of mat, drinking was associated with the risk of all UADT cancers, the association with cumulative mat, consumption was restricted to esophageal cancer (p-value of linear trend 0.006). The analyses of temperature at which mat, was drunk were not conclusive. The increased risk associated with mat, drinking was more evident in never-smokers and never-alcohol drinkers than in other individuals. Our study strengthens the evidence of an association between mat, drinking and esophageal cancer; the hypothesis of an association with other UADT cancers remains to be clarified. (AU)

Processo FAPESP: 01/01768-2 - Estudo internacional de fatores ambientais, vírus e câncer de cavidade oral e de laringe
Beneficiário:José Eluf Neto
Linha de fomento: Auxílio à Pesquisa - Regular