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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Upper arm circumference is an independent predictor of left ventricular concentric hypertrophy in hypertensive women

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Autor(es):
Pio-Magalhaes, Jose A. [1] ; Cornelio, Marilia [1] ; Leme, Jr., Cid A. [2] ; Matos-Souza, Jose R. [2] ; Garlipp, Celia R. [3] ; Gallani, Maria C. J. [1] ; Rodrigues, Roberta C. [1] ; Franchini, Kleber G. [2] ; Nadruz, Jr., Wilson [2]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Sch Med, Dept Nursing, Campinas, SP - Brazil
[2] Univ Estadual Campinas, Sch Med, Dept Internal Med, Campinas, SP - Brazil
[3] Univ Estadual Campinas, Sch Med, Dept Clin Pathol, Campinas, SP - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: HYPERTENSION RESEARCH; v. 31, n. 6, p. 1177-1183, JUN 2008.
Citações Web of Science: 10
Resumo

Upper arm circumference (UAC) measurement is necessary for the proper sizing of cuffs and is recommended for accurate blood pressure (BP) assessment. The aim of this report is to identify and quantify the relationships between UAC and the usual anthropometric measurements of body fat distribution and cardiac structure in hypertensive subjects. We evaluated 339 patients (202 women and 137 men) by medical history, physical examination, anthropometry, metabolic and inflammatory parameters, and echocardiography. Partial correlation analyses adjusted for age and body mass index revealed that anthropometric variables were significantly associated with echocardiographic parameters exclusively in women. In this regard, UAC correlated with interventricular septum thickness, posterior wall thickness, and relative wall thickness >= 0.45, while waist circumference was related to left cardiac chamber diameter. Multivariate analyses including age, body mass index, systolic BP, homeostasis model assessment index, and use of antihypertensive medications demonstrated that UAC was an independent predictor of left ventricular wall thickness and concentric hypertrophy in women. Further linear regression analyses revealed that waist circumference was an independent predictor of left ventricular end-diastolic and left atrial diameters in this gender. Overall, these findings suggest that UAC determination might serve not only as a routine approach preceding BP evaluation but also as a simple and feasible predictor of adverse LV remodeling in hypertensive women. (AU)

Processo FAPESP: 05/56986-5 - Mecanotransdução vascular: implicações na aterogênese
Beneficiário:Wilson Nadruz Junior
Linha de fomento: Auxílio à Pesquisa - Apoio a Jovens Pesquisadores