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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Evaluation of an Experimental Gel Containing Euclea natalensis: An In Vitro Study

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Autor(es):
de Carvalho Sales-Peres, Silvia Helena [1] ; de Freitas Brianezzi, Leticia Ferreira [1] ; Marsicano, Juliane Avansini [1] ; Forim, Moacir Rossi [2] ; da Silva, Maria Fatima das Gracas Fernandes [2] ; Sales-Peres, Arsenio [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Dept Pediat Dent Orthodont & Publ Hlth, Bauru Sch Dent, BR-17012901 Bauru, SP - Brazil
[2] Univ Fed Sao Carlos, Lab Nat Prod, Dept Chem, BR-13565905 Sao Carlos, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Evidence-based Complementary and Alternative Medicine; 2012.
Citações Web of Science: 5
Resumo

Objective. To evaluate the effect of an experimental gel containing Euclea natalensis extract on dentin permeability. Methods. Thirty-six dentin discs, 1-mm-thick. The discs were prepared from the coronal dentin of extracted human third molars that were divided into 3 groups (n = 10). The dentin discs in each group were treated with the groups following experimental materials: (FG): 1.23% fluoride gel, pH 4.1; (EG): Euclea natalensis extract gel, pH 4.1; (CG): control gel, pH 4.1. The gels were applied to the occlusal slide of the dentin under the following conditions: after 37% phosphoric acid and before 6% citric acid. The hydraulic conductance (HC) of each condition was determined four times using a fluid flow apparatus (Flodec). The data were analyzed using Two-way ANOVA and Tukey's test (P < 0.05). Results. The greatest mean reduction in HC was produced in group EG dentin discs (61.2%; P < 0.05). Even after acid challenge with 6% citric acid the great reduction occurred in group EG (66.0%; P < 0.05) than other groups (CG-77.1%, FG-90.8%). Conclusion. E. natalensis gel not only reduced dentin permeability, but also resisted posttreatment citric acid challenge without changing its permeability. Further research has to confirm this promising result in the clinical situation. (AU)

Processo FAPESP: 10/09951-0 - Avaliação in vitro do potencial de um gel contendo Euclea natalensis na redução da erosão dentária e na permeabilidade dentinária
Beneficiário:Silvia Helena de Carvalho Sales Peres
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 09/16079-0 - Avaliação in vitro do potencial de um gel contendo Euclea natalensis na redução da permeabilidade dentinária
Beneficiário:Leticia Ferreira de Freitas Brianezzi
Linha de fomento: Bolsas no Brasil - Iniciação Científica