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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Whey protein hydrolysate enhances the exercise-induced heat shock protein (HSP70) response in rats

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Autor(es):
de Moura, Carolina Soares [1] ; Barboza Lollo, Pablo Christiano [1] ; Morato, Priscila Neder [1] ; Carneiro, Everardo Magalhaes [2] ; Amaya-Farfan, Jaime [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Fac Food Engn, Dept Food & Nutr, Sao Paulo - Brazil
[2] Univ Estadual Campinas, Inst Biol, Dept Physiol & Biophys, Sao Paulo - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Food Chemistry; v. 136, n. 3-4, p. 1350-1357, FEB 1 2013.
Citações Web of Science: 19
Resumo

Whey protein has been suggested to be potential protective agent against various forms of stress. The heat shock protein HSP70 confers greater cellular tolerance against stressors. The present study evaluated the effects of whey protein intake on HSP70 expression. Forty-eight male Wistar rats were divided into sedentary and exercised groups, and each group was fed as a protein source casein (CAS), whey protein (WP) or whey protein hydrolysate (WPH) for 3 weeks. Exercise on a treadmill was used as the source of stress in the animals from the exercised group. The results showed a larger increase in HSP70 expression in the soleus, gastrocnemius and lung of the WPH-fed rats than WP or casein-fed rats. HSP70 expression in the sedentary rats was very low, independent of the diet or tissue. Protein carbonyls were lower in the group that consumed WPH. These data suggest that the consumption of WPH enhances HSP70 expression. (C) 2012 Elsevier Ltd. All rights reserved. (AU)

Processo FAPESP: 10/02419-0 - Efeito do consumo de hidrolisado do soro de leite no metabolismo energético e estado redox em ratos exercitados
Beneficiário:Jaime Amaya Farfan
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 11/13035-1 - Efeito do consumo das proteínas do soro do leite nos biomarcadores HSP e parâmetros bioquímicos em ratos
Beneficiário:Jaime Amaya Farfan
Linha de fomento: Auxílio à Pesquisa - Regular