Morphological analysis and cell viability on diamond-like carbon films containing nanocrystalline diamond particles

Autor(es)

Almeida, C. N. ^[1] ; Ramos, B. C. ^[1] ; Da-Silva, N. S. ^[2] ; Pacheco-Soares, C. ^[2] ; Trava-Airoldi, V. J. ^[3] ; Lobo, A. O. ^[1] ; Marciano, F. R. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Vale do Paraiba Univap, Lab Biomed Nanotechnol NanoBio, BR-12244000 Sao Jose Dos Campos, SP - Brazil

^[2] Univ Vale do Paraiba Univap, Lab Biol Celular & Tecidual, BR-12244000 Sao Jose Dos Campos, SP - Brazil

^[3] Inst Nacl Pesquisas Espaciais INPE, Associated Lab Sensors & Mat, BR-12227010 Sao Jose Dos Campos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Applied Surface Science; v. 275, p. 258-263, JUN 15 2013.
• Citações Web of Science: 3

Resumo

The coating of orthopedic prostheses with diamond like-carbon (DLC) has been actively studied in the past years, in order to improve mechanical, tribological properties and promote the material's biocompatibility. Recently, the incorporation of crystalline diamond nanoparticles into the DLC film has shown effective in combating electrochemical corrosion in acidic medias. This study examines the material's biocompatibility through testing by LDH release and MTT, on in vitro fibroblasts; using different concentrations of diamond nanoparticles incorporated into the DLC film. Propounding its potential use in orthopedics in order to increase the corrosion resistance of prostheses and improve their relationship with the biological environment. (C) 2013 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 11/20345-7 - Estudo de filmes de carbono-tipo diamante contendo nanopartículas incorporadas para aplicações biomédicas
• Beneficiário: Fernanda Roberta Marciano
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 11/17877-7 - Desenvolvimento de novos scaffolds poliméricos por eletrofiação com incorporação de nanotubos alinhados e nanohidroxiapatita para regeneração óssea
• Beneficiário: Anderson de Oliveira Lobo
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores