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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

IRRITABLE MOOD IN ADULT MAJOR DEPRESSIVE DISORDER: RESULTS FROM THE WORLD MENTAL HEALTH SURVEYS

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Autor(es):
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Kovess-Masfety, Viviane [1, 2] ; Alonso, Jordi [3, 4] ; Angermeyer, Matthias [5] ; Bromet, Evelyn [6] ; Girolamo, Giovanni De [7] ; de Jonge, Peter [8] ; Demyttenaere, Koen [9] ; Florescu, Silvia E. [10] ; Gruber, Michael J. [11] ; Gureje, Oye [12] ; Hu, Chiyi [13, 14] ; Huang, Yueqin [15] ; Karam, Elie G. [16] ; Jin, Robert [17] ; Lepine, Jean-Pierre [18] ; Levinson, Daphna ; McLaughlin, Katie A. ; Medina-Mora, Maria E. ; O'Neill, Siobhan ; Ono, Yutaka ; Posada-Villa, Jose A. ; Sampson, Nancy A. [11] ; Scott, Kate M. ; Shahly, Victoria [11] ; Stein, Dan J. ; Viana, Maria C. ; Zarkov, Zahari ; Kessler, Ronald C. [11]
Número total de Autores: 28
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[1] Univ Paris 05, F-75181 Paris 04 - France
[2] EHESP Sch Publ Hlth, Dept Epidemiol, F-75181 Paris 04 - France
[3] IMIM Hosp del Mar Res Inst, Hlth Serv Res Unit, Barcelona - Spain
[4] CIBER Epidemiol & Salud Publ CIBERESP, Barcelona - Spain
[5] Ctr Publ Mental Hlth, Gosing Am Wagram - Austria
[6] SUNY Stony Brook, Dept Psychiat, Stony Brook, NY 11794 - USA
[7] IRCCS Ctr S Giovanni di Dio Fatebenefratelli, Bologna - Italy
[8] Univ Groningen, Univ Med Ctr Groningen, NL-9713 AV Groningen - Netherlands
[9] Univ Hosp, Univ Hosp Gasthuisberg, Dept Psychiat, Louvain - Belgium
[10] Natl Sch Publ Hlth & Hlth Serv Management, Publ Hlth Res & Evidence Based Med Dept, Bucharest - Romania
[11] Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 - USA
[12] Univ Coll Hosp, Dept Psychiat, Ibadan - Nigeria
[13] Shenzhen Inst Mental Hlth, Shenzhen - Peoples R China
[14] Shenzhen Kangning Hosp, Shenzhen - Peoples R China
[15] Peking Univ, Inst Mental Hlth, Beijing 100871 - Peoples R China
[16] St George Hosp Univ, Med Ctr, Dept Psychiat & Clin Psychol, Inst Dev Res Advocacy & Appl Care IDRAAC, Beirut - Lebanon
[17] Harvard Pilgrim Hlth Care Inst, Dept Populat Med, Boston, MA - USA
[18] Hop Lariboisiere Fernand Widal, Paris - France
Número total de Afiliações: 18
Tipo de documento: Artigo Científico
Fonte: DEPRESSION AND ANXIETY; v. 30, n. 4, p. 395-406, APR 2013.
Citações Web of Science: 9
Resumo

Background Although irritability is a core symptom of DSM-IV major depressive disorder (MDD) for youth but not adults, clinical studies find comparable rates of irritability between nonbipolar depressed adults and youth. Including irritability as a core symptom of adult MDD would allow detection of depression-equivalent syndromes with primary irritability hypothesized to be more common among males than females. We carried out a preliminary examination of this issue using cross-national community-based survey data from 21 countries in the World Mental Health (WMH) Surveys (n = 110,729). Methods The assessment of MDD in the WHO Composite International Diagnostic Interview includes one question about persistent irritability. We examined two expansions of the definition of MDD involving this question: (1) cases with dysphoria and/or anhedonia and exactly four of nine Criterion A symptoms plus irritability; and (2) cases with two or more weeks of irritability plus four or more other Criterion A MDD symptoms in the absence of dysphoria or anhedonia. Results Adding irritability as a tenth Criterion A symptom increased lifetime prevalence by 0.4% (from 11.2 to 11.6%). Adding episodes of persistent irritability increased prevalence by an additional 0.2%. Proportional prevalence increases were significantly higher, but nonetheless small, among males compared to females. Rates of severe role impairment were significantly lower among respondents with this irritable depression who did not meet conventional DSM-IV criteria than those with DSM-IV MDD. Conclusion Although limited by the superficial assessment in this single question on irritability, results do not support expanding adult MDD criteria to include irritable mood. (AU)

Processo FAPESP: 03/00204-3 - Estudo epidemiológico dos transtornos psiquiátricos na região metropolitana de São Paulo: prevalências, fatores de risco e sobrecarga social e econômica
Beneficiário:Laura Helena Silveira Guerra de Andrade Burdmann
Linha de fomento: Auxílio à Pesquisa - Temático