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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

One-Visit Versus Two-Visit Root Canal Treatment: Effectiveness in the Removal of Endotoxins and Cultivable Bacteria

Texto completo
Autor(es):
Xavier, Ana Claudia C. [1] ; Martinho, Frederico C. [1] ; Chung, Adriana [1] ; Oliveira, Luciane D. [1] ; Jorge, Antonio O. C. [1] ; Valera, Marcia C. [1] ; Carvalho, Claudio A. T. [1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Estadual Paulista, UNESP, Sao Jose dos Campos Dent Sch, Dept Restorat Dent, Endodont Div, Sao Jose Dos Campos, SP - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF ENDODONTICS; v. 39, n. 8, p. 959-964, AUG 2013.
Citações Web of Science: 27
Resumo

Introduction: This clinical study was conducted to compare the effectiveness of 1-visit versus 2-visit root canal treatment in removing endotoxins and cultivable bacteria from primarily infected root canals. Methods: Forty-eight primarily infected root canals were selected and randomly divided into 4 groups: G1, 1% NaOCl; G2, 2% chlorhexidine (CHX) gel; 63, 1% NaOCl + Ca(OH)(2); and G4, 2% CHX gel + Ca(OH)(2) (all, n = 12). G1 and G2 involved 1-visit treatment, whereas G3 and 64 involved 2-visit treatment with the placement of Ca(OH)(2) medication for 14 days. Samples were collected before and after root canal procedures. A chromogenic LAL assay test was used to quantify endotoxins. Culture techniques were used to determine bacterial counts. Results: Endotoxins and cultivable bacteria were detected in 100% of the initial samples. All treatment protocols were effective in reducing bacterial load from infected root canals: G1 (1% NaOCl, 99.97%), G2 (2% CHX gel, 99.75%), G3 (1% NaOCl + Ca(OH)(2), 99.90%), and 64 (2% CHX gel + Ca(OH)(2), 96.81%), respectively (P < .05). No differences were found in bacterial load reduction when comparing 1-visit and 2-visit treatment groups, irrespective of the irrigant tested (P > .05). Higher median percentage values of endotoxin reduction were achieved in the 2-visit treatment groups (G3, 98.01% and 64, 96.81%) compared with 1-visit treatment groups (G1, 86.33% and G2, 84.77%) (all P < .05). Conclusions: Both 1-Visit and 2-visit root canal treatment protocols were effective in reducing bacteria and endotoxins, but they were not able to eliminate them in all root canals analyzed. Furthermore, 2-visit root canal treatment protocols were more effective in reducing endotoxins than 1-visit root canal treatment protocols. (AU)

Processo FAPESP: 12/19536-5 - Investigação de biomarcadores potenciais no diagnóstico da pneumonia em pacientes sob ventilação mecânica invasiva
Beneficiário:Frederico Canato Martinho
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 09/54621-0 - Identificacao de microrganismos, quantificacao de endotoxinas e avaliacao in vivo do extrato glicolico de propolis em dentes com necrose pulpar e lesao periapical.
Beneficiário:Cláudio Antonio Talge Carvalho
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 08/54536-0 - Estudo in vivo da acao do tratamento endodontico sobre endotoxinas e metaloproteinases da matriz (mmp) em canais radiculares com polpa necrosada e avaliacao dos efeitso citotoxicos
Beneficiário:Cláudio Antonio Talge Carvalho
Linha de fomento: Auxílio à Pesquisa - Regular