Shape, connectedness and dynamics in neuronal networks

Autor(es)

Comin, Cesar Henrique ^[1] ; Costa, Luciano da Fontoura ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Fis Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: JOURNAL OF NEUROSCIENCE METHODS; v. 220, n. 2, SI, p. 100-115, NOV 15 2013.
• Citações Web of Science: 4

Resumo

The morphology of neurons is directly related to several aspects of the nervous system, including its connectedness, health, development, evolution, dynamics and, ultimately, behavior. Such interplays of the neuronal morphology can be understood within the more general shape-function paradigm. The current article reviews, in an introductory way, some key issues regarding the role of neuronal morphology in the nervous system, with emphasis on works developed in the authors' group. The following topics are addressed: (a) characterization of neuronal shape; (b) stochastic synthesis of neurons and neuronal systems; (c) characterization of the connectivity of neuronal networks by using complex networks concepts; and (d) investigations of influences of neuronal shape on network dynamics. The presented concepts and methods are useful also for several other multiple object systems, such as protein-protein interaction, tissues, aggregates and polymers. (C) 2013 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 11/22639-8 - Estudo da relação estrutura-dinâmica em redes modulares
• Beneficiário: Cesar Henrique Comin
• Linha de fomento: Bolsas no Brasil - Doutorado
• Processo FAPESP: 11/50761-2 - Modelos e métodos de e-Science para ciências da vida e agrárias
• Beneficiário: Roberto Marcondes Cesar Junior
• Linha de fomento: Auxílio à Pesquisa - Temático