Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Molecular phylogeography of tick-borne encephalitis virus in central Europe

Texto completo
Autor(es):
Mostrar menos -
Weidmann, Manfred [1] ; Frey, Stefan [2] ; Freire, Caio C. M. [3] ; Essbauer, Sandra [2] ; Ruzek, Daniel [4, 5] ; Klempa, Boris [6, 7] ; Zubrikova, Dana [8] ; Voegerl, Maria [9] ; Pfeffer, Martin [10] ; Hufert, Frank T. [1] ; Zanotto, Paolo M. [3] ; Dobler, Gerhard [2]
Número total de Autores: 12
Afiliação do(s) autor(es):
[1] Univ Med Ctr, Dept Virol, D-37075 Gottingen - Germany
[2] Bundeswehr Inst Microbiol, D-80937 Munich - Germany
[3] Univ Sao Paulo, Dept Microbiol, Biomed Sci Inst ICB 2, BR-05508000 Sao Paulo - Brazil
[4] Vet Res Inst, Dept Virol, CZ-62100 Brno - Czech Republic
[5] Acad Sci Czech Republic, Inst Parasitol, Ctr Biol, CZ-37005 Ceske Budejovice - Czech Republic
[6] Slovak Acad Sci, Inst Virol, Bratislava 84505 - Slovakia
[7] Charite, Inst Virol, Berlin - Germany
[8] Slovak Acad Sci, Inst Parasitol, Kosice - Slovakia
[9] Univ Munich, Fac Vet Med, Munich - Germany
[10] Univ Leipzig, Inst Anim Hyg & Vet Publ Hlth, D-04109 Leipzig - Germany
Número total de Afiliações: 10
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF GENERAL VIROLOGY; v. 94, n. 9, p. 2129-2139, SEP 2013.
Citações Web of Science: 22
Resumo

In order to obtain a better understanding of tick-borne encephalitis virus (TBEV) strain movements in central Europe the E gene sequences of 102 TBEV strains collected from 1953 to 2011 at 38 sites in the Czech Republic, Slovakia, Austria and Germany were determined. Bayesian analysis suggests a 350-year history of evolution and spread in central Europe of two main lineages, A and B. In contrast to the east to west spread at the Eurasian continent level, local central European spreading patterns suggest historic west to east spread followed by more recent east to west spread. The phylogenetic and network analyses indicate TBEV ingressions from the Czech Republic and Slovakia into Germany via landscape features (Danube river system), biogenic factors (birds, red deer) and anthropogenic factors. The identification of endemic foci showing local genetic diversity is of paramount importance to the field as these will be a prerequisite for in-depth analysis of focal TBEV maintenance and long-distance TBEV spread. (AU)

Processo FAPESP: 10/19341-4 - Caracterização biológica de recombinantes naturais e artificiais entre os subtipos B e F de HIV-1
Beneficiário:Paolo Marinho de Andrade Zanotto
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 11/17120-3 - Análise da diversidade genética de populações do nucleopoliedrovírus Anticarsia gemmatalis (AgMNPV) isoladas em diferentes regiões geográficas
Beneficiário:Paolo Marinho de Andrade Zanotto
Linha de fomento: Auxílio à Pesquisa - Regular