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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Development of a Lipid Particle for beta-Carotene Encapsulation Using a Blend of Tristearin and Sunflower Oil: Choice of Lipid Matrix and Evaluation of Shelf Life of Dispersions

Autor(es):
Gomes, Graziela V. L. [1] ; Simplicio, Izabella A. S. [1] ; Souto, Eliana B. [2, 3] ; Cardoso, Lisandro P. [4] ; Pinho, Samantha C. [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Fac Anim Sci & Food Engn, Dept Food Engn, BR-13635900 Pirassununga, SP - Brazil
[2] Fernando Pessoa Univ FCS UFP, Fac Hlth Sci, P-4200150 Oporto - Portugal
[3] Univ Tras Os Montes & Alto Douro CGB UTAD IBB, Ctr Genom & Biotechnol, Inst Biotechnol & Bioengn, P-5001801 Vila Real - Portugal
[4] Univ Estadual Campinas, UNICAMP, Inst Phys Gleb Wataghin, Dept Appl Phys, BR-13083859 Campinas, SP - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: Food Technology and Biotechnology; v. 51, n. 3, p. 383-391, JUL-SEP 2013.
Citações Web of Science: 9
Resumo

Solid lipid particles are colloidal carriers that have been studied for almost 20 years in the pharmaceutical field and recently have been investigated by food researchers due to their capacity to enhance the incorporation of lipophilic bioactives and their bioavailability in aqueous formulations. The aims of this study are to choose a suitable lipid matrix to produce solid lipid particles, which would be used to encapsulate beta-carotene, and to evaluate the capacity of dispersions to protect the incorporated carotenoid. Bulk lipid mixtures of tristearin and sunflower oil were analysed by differential scanning calorimetry and wide angle X-ray diffraction, and the mixture with the highest degree of structural disorganisation was chosen. beta-Carotene was then encapsulated in solid lipid particles produced with this mixture, composed of 70 % tristearin and 30 % sunflower oil (6 % total lipid) and stabilised with hydrogenated soy lecithin and Tween 80 (3 % total surfactant) by hot pressure homogenisation. Two types of particles were produced, using one or two passages in the homogenisation step. Average particle size, zeta potential, thermal behaviour, crystallinity and beta-carotene concentration were monitored over 4 months of storage (under refrigerated conditions). The results showed minor differences between the systems in terms of size distribution, although the particles produced with one passage through the homogeniser were slightly more efficient at protecting the beta-carotene from degradation and also suffered few microstructural alterations after 4 months. (AU)

Processo FAPESP: 09/02028-4 - Incorporação de beta-caroteno em sistemas lipídicos sólidos micro e nanoparticulados: produção, estbilidade e caracterização microestrutural
Beneficiário:Graziela Veiga de Lara Gomes
Linha de fomento: Bolsas no Brasil - Mestrado