Fast preparation of nano-hydroxyapatite/superhydrophilic reduced graphene oxide composites for bioactive applications

Autor(es)

Zanin, Hudson ^[1] ; Saito, Eduardo ^[1] ; Marciano, Fernanda Roberta ^[2] ; Ceragioli, Helder Jose ^[3] ; Campos Granato, Alessandro Eustaquio ^[4] ; Porcionatto, Marimelia ^[4] ; Lobo, Anderson Oliveira ^[2]

Afiliação do(s) autor(es)

^[1] Natl Inst Space Res, Associated Lab Sensors & Mat, BR-12227010 Sao Jose Dos Campos, SP - Brazil

^[2] Univ Vale do Paraiba, Inst Res & Dev, Lab Biomed Nanotechnol, BR-12244000 Sao Jose Dos Campos, SP - Brazil

^[3] Univ Estadual Campinas, Dept Semicond Instrumentos & Foton, BR-13083852 Campinas, SP - Brazil

^[4] Univ Fed Sao Paulo, Neurobiol Lab, BR-04039032 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF MATERIALS CHEMISTRY B; v. 1, n. 38, p. 4947-4955, 2013.
• Citações Web of Science: 39

Resumo

A method for the direct electrodeposition of globular nano-hydroxyapatite (nHAp) onto reduced graphene oxide (RGO) is presented and a model for the specific growth preference is discussed. Results show that the carboxyl (carboxylic acid)/carboxylate functional groups attached directly to the RGO after oxygen plasma treatment were essential to accelerate the OH- formation and the deposition of globular nHAp crystals. High resolution scanning electron microscopy, energy dispersive X-ray and X-ray diffraction showed that homogeneous, highly crystalline, stoichiometric nHAp crystals, with preferential growth in the (002) plane direction, were formed without any thermal treatment. The nHAp/RGO composites were shown to be an appropriate surface for mesenchymal stem cell adhesion with active formation of membrane projections. (AU)

• Processo FAPESP: 11/20345-7 - Estudo de filmes de carbono-tipo diamante contendo nanopartículas incorporadas para aplicações biomédicas
• Beneficiário: Fernanda Roberta Marciano
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 11/17877-7 - Desenvolvimento de novos scaffolds poliméricos por eletrofiação com incorporação de nanotubos alinhados e nanohidroxiapatita para regeneração óssea
• Beneficiário: Anderson de Oliveira Lobo
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores