Candida albicans adherence to an acrylic resin mod... - BV FAPESP
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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Candida albicans adherence to an acrylic resin modified by experimental photopolymerised coatings: an in vitro study

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Autor(es):
Lazarin, Andrea Azevedo [1] ; Zamperini, Camila Andrade [1] ; Vergani, Carlos Eduardo [1] ; Wady, Amanda Fucci [1] ; Giampaolo, Eunice Teresinha [1] ; Machado, Ana Lucia [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] UNESP Univ Estadual Paulista, Araraquara Dent Sch, Dept Dent Mat & Prosthodont, BR-14801903 Sao Paulo - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: GERODONTOLOGY; v. 31, n. 1, p. 25-33, MAR 2014.
Citações Web of Science: 8
Resumo

PurposeThis study evaluated whether photopolymerised coatings containing zwitterion or hydrophilic monomers would reduce the adhesion of Candida albicans to an acrylic resin. Materials and methodsDisc-shaped samples (n=468) were fabricated with rough or smooth surfaces. The samples did not receive any surface treatment (control) or were coated with one of the following experimental coatings (2-hydroxyethyl methacrylate - HE; 3-hydroxypropyl methacrylate - HP; and 2-trimethylammonium ethyl methacrylate chloride - T; and sulfobetaine methacrylate - S). The concentrations of the constituent monomers were 25, 30 or 35%. The water contact angles of the samples were measured, and half of the samples were exposed to saliva. The adherent yeast cells were counted after crystal violet staining. ResultsFor the smooth samples, the groups S35, HP35 and HE35 showed significantly lower number of adhered Candida than control, in the absence of saliva. There were no significant differences among the experimental and control groups for the rough samples, but the saliva decreased the cell numbers for groups S25, S30 and HP30. The photoelectron spectroscopy analysis confirmed the changes in the chemical compositions of the experimental samples. ConclusionsThe experimental photopolymerised coatings changed the chemical composition and decreased C.albicans adhesion in the groups S35, HP35 and HE35, suggesting that they should be further investigated. (AU)

Processo FAPESP: 06/06842-0 - Efetividade de vernizes fotopolimerizáveis experimentais na redução da hidrofobicidade e adesão de Candida albicans em uma resina para base de próteses
Beneficiário:Ana Lucia Machado
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 06/00435-3 - Efetividade de vernizes fotopolimerizáveis experimentais na redução da hidrofobicidade e adesão de Candida albicans em uma resina para base de prótese
Beneficiário:Andréa Azevedo Lazarin
Modalidade de apoio: Bolsas no Brasil - Doutorado