Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Electrochemical determination of estradiol using a thin film containing reduced graphene oxide and dihexadecylphosphate

Texto completo
Autor(es):
Janegitz, Bruno C. [1] ; dos Santos, Fabricio A. [1] ; Faria, Ronaldo C. [2] ; Zucolotto, Valtencir [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Nanomed & Nanotoxicol Grp, Inst Fis Sao Carlos, BR-13566390 Sao Carlos, SP - Brazil
[2] Univ Fed Sao Carlos, Dept Quim, BR-13565970 Sao Carlos, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Materials Science & Engineering C-Materials for Biological Applications; v. 37, p. 14-19, APR 1 2014.
Citações Web of Science: 32
Resumo

Graphene is a material that has attracted attention with regard to sensing and biosensing applications in recent years. Here, we report a novel treatment (using ultrasonic bath and ultrasonic tip) to obtain graphene oxide (GO) and a new stable conducting film using reduced graphene oxide (RGO) and dihexadecylphosphate film (DHP). The GO was obtained by chemical exfoliation and it was reduced using NaBH4. Subsequently, RGO-DHP dispersion was prepared and it was dropped onto a glassy carbon electrode by casting technique. The electrode was characterized by cyclic voltammetry and electrochemical spectroscopy impedance. The voltammetric behavior of the RGO-DHP/GC electrode in the presence of estradiol was studied, and the results reported an irreversible oxidation peak current at 0.6 V. Under the optimal experimental conditions, using linear sweep adsorptive stripping voltammetry, the detection limit obtained for this hormone was 7.7 x 10(-8) mol L-1. The proposed electrode can be attractive for applications as electrochemical sensors and biosensors. (C) 2014 Elsevier B.V. All rights reserved. (AU)

Processo FAPESP: 12/02877-4 - Desenvolvimento de novos biossensores utilizando materiais nanoestruturados ativos
Beneficiário:Bruno Campos Janegitz
Linha de fomento: Bolsas no Brasil - Pós-Doutorado