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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Dietary polyunsaturated fatty acid intake during late pregnancy affects fatty acid composition of mature breast milk

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Autor(es):
Nishimura, Renata Y. [1] ; Barbieiri, Patricia [1] ; de Castro, Gabriela S. F. [2] ; Jordao, Jr., Alceu A. [3] ; Castro Perdonda, Gleici da Silva [4] ; Sartorelli, Daniela S. [4]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Ribeirao Preto Med Sch, Program Community Hlth, Sao Paulo - Brazil
[2] Univ Sao Paulo, Ribeirao Preto Med Sch, Program Internal Med, Sao Paulo - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Sao Paulo - Brazil
[4] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Social Med, Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: NUTRITION; v. 30, n. 6, p. 685-689, JUN 2014.
Citações Web of Science: 11
Resumo

Objective: The aim of this study was to investigate how maternal polyunsaturated fatty acid intake at different periods during pregnancy affects the composition of polyunsaturated fatty acids in mature human milk. Methods: A prospective study was conducted involving 45 pregnant women, aged between 18 and 35y, who had full-term pregnancies and practiced exclusive or predominant breast-feeding. Mature breast milk samples were collected after the 5th postpartum week by manual expression; fatty acid composition was determined by gas chromatography. Fatty acid intake during pregnancy and puerperium was estimated through multiple 24-h dietary recalls. Linear regression models, adjusted by postpartum body mass index and deattenuated, were used to determine associations between estimated fatty acids in maternal diet during each trimester of pregnancy and fatty acid content in mature human milk. Results: A positive association was identified between maternal intake of eicosapentaenoic acid (beta, 1.873; 95% confidence interval {[}CI], 0.545, 3.203) and docosahexaenoic acid (beta, 0.464; 95% CI, 0.212-0.714) during the third trimester of pregnancy, as well as the maternal dietary omega-3 to omega-6 ratio (beta, 0.093; 95% CI, 0.016-0.170) during the second and third trimesters and postpartum period, with these fatty acids content in mature breast milk. Conclusions: The maternal dietary docosahexaenoic acid and eicosapentaenoic acid content during late pregnancy may affect the fatty acid composition of mature breast milk. Additionally, the maternal dietary intake of omega-3 to omega-6 fatty acid ratio, during late pregnancy and the postpartum period, can affect the polyunsaturated fatty acid composition of breast milk. (C) 2014 Elsevier Inc. All rights reserved. (AU)

Processo FAPESP: 10/12320-1 - Influência do consumo alimentar materno na composição lipídica do leite humano maduro
Beneficiário:Renata Yumi Nishimura
Linha de fomento: Bolsas no Brasil - Mestrado
Processo FAPESP: 10/00408-1 - Efeitos dos ácidos graxos n-3 provenientes do óleo de peixe no metabolismo lipídico e expressão gênica de ratos alimentados com dieta rica em frutose
Beneficiário:Gabriela Salim Ferreira de Castro
Linha de fomento: Bolsas no Brasil - Doutorado