Structure- and ligand based-drug design of new chemotherapeutic agents for the treatment of cancer

• Grant number: 10/06741-4
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: August 01, 2010
• End date: August 31, 2015
• Field of knowledge: Biological Sciences - Biophysics - Molecular Biophysics
• Principal Investigator: Adriano Defini Andricopulo
• Grantee: Ricardo Nascimento dos Santos
• Host Institution: Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Associated scholarship(s): 13/11950-0 - Structural studies of microtubule polymerization dynamics and its modulation by the action of anticancer drugs, BE.EP.DD

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ALTEI, WANESSA F.; PACHANE, BIANCA C.; MARTINS, LUCIMARA J.; GOMES, RALPH C.; SANTOS, RICARDO N.; FERNANDES, DANIARA C.; SELISTRE-DE-ARAUJO, HELOISA S.; COELHO, FERNANDO; ANDRICOPULO, ADRIANO D.. Synthetic Spirocyclohexadienones as New Anti-Migratory Compounds in Triple-Negative Breast Cancer Cell Migration. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, v. 21, n. 14, p. 1901-1910, 2021. (13/07600-3, 19/11437-7, 10/06741-4)

VALLI, MARILIA; ALTEI, WANESSA; DOS SANTOS, RICARDO N.; DE LUCCA, JR., EMILIO C.; DESSOY, MARCO A.; PIOLI, RENAN M.; COTINGUIBA, FERNANDO; CACHET, XAVIER; MICHEL, SYLVIE; FURLAN, MAYSA; et al. Synthetic Analogue of the Natural Product Piperlongumine as a Potent Inhibitor of Breast Cancer Cell Line Migration. Journal of the Brazilian Chemical Society, v. 28, n. 3, SI, p. 475-484, MAR 2017. (10/06741-4, 10/17329-7, 03/02176-7, 13/07600-3)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SANTOS, Ricardo Nascimento dos. Design of microtubule polymerization modulators with anticancer properties, structural analysis of macromolecules and development of a virtual database of natural products. 2015. Doctoral Thesis - Universidade de São Paulo (USP). Instituto de Física de São Carlos (IFSC/BT) São Carlos.