Effects of caloric restriction on mitochondrial morphology, dynamics, bioenergetics and redox state

• Grant number: 13/04871-6
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: May 01, 2013
• End date: March 31, 2016
• Field of knowledge: Biological Sciences - Biochemistry - Metabolism and Bioenergetics
• Principal Investigator: Alicia Juliana Kowaltowski
• Grantee: Maria Fernanda Pereira de Araújo Demonte Forni
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 10/51906-1 - Mitochondrial bioenergetics, ion transport, redox state and DNA metabolism, AP.TEM

Abstract

Pretende-se estudar o efeito de soros de animais em restrição calórica sobre culturas de células, para avaliar os resultados e vias de sinalização envolvidos em modificações de funções bioenergéticas, quantidade e estrutura mitocondriais e balanço redox. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FORNI, MARIA FERNANDA; PELOGGIA, JULIA; TRUDEAU, KYLE; SHIRIHAI, ORIAN; KOWALTOWSKI, ALICIA J.. Murine Mesenchymal Stem Cell Commitment to Differentiation Is Regulated by Mitochondrial Dynamics. Stem Cells, v. 34, n. 3, p. 743-755, MAR 2016. (10/51906-1, 13/04871-6, 13/07937-8, 14/17270-3)

FORNI, MARIA FERNANDA; CHAUSSE, BRUNO; PELOGGIA, JULIA; KOWALTOWSKI, ALICIA J.. Bioenergetic profiling in the skin. EXPERIMENTAL DERMATOLOGY, v. 25, n. 2, p. 147-148, FEB 2016. (10/51906-1, 13/04871-6, 13/07937-8, 14/17270-3)

LUEVANO-MARTINEZ, LUIS ALBERTO; FORNI, MARIA FERNANDA; DOS SANTOS, VALQUIRIA TIAGO; SOUZA-PINTO, NADJA C.; KOWALTOWSKI, ALICIA J.. Cardiolipin is a key determinant for mtDNA stability and segregation during mitochondrial stress. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, v. 1847, n. 6-7, p. 587-598, JUN-JUL 2015. (10/51906-1, 10/18254-0, 13/04919-9, 13/04871-6, 13/07937-8)

TEOFILO SATURI DE CARVALHO, ANA ELISA; BASSANEZE, VINICIUS; FORNI, MARIA FERNANDA; KEUSSEYAN, ALINE ALFONSO; KOWALTOWSKI, ALICIA JULIANA; KRIEGER, JOSE EDUARDO. Early Postnatal Cardiomyocyte Proliferation Requires High Oxidative Energy Metabolism. SCIENTIFIC REPORTS, v. 7, NOV 13 2017. (12/10109-7, 13/17368-0, 13/04871-6, 13/26440-7, 11/19678-1, 15/25776-7, 13/07937-8)

LUEVANO-MARTINEZ, LUIS ALBERTO; FORNI, MARIA FERNANDA; PELOGGIA, JULIA; WATANABE, II-SEI; KOWALTOWSKI, ALICIA J.. Calorie restriction promotes cardiolipin biosynthesis and distribution between mitochondrial membranes. MECHANISMS OF AGEING AND DEVELOPMENT, v. 162, p. 9-17, MAR 2017. (13/07937-8, 13/04871-6, 13/04919-9)

FORNI, MARIA FERNANDA; PELOGGIA, JULIA; BRAGA, TARCIO T.; ORTEGA CHINCHILLA, JESUS EDUARDO; SHINOHARA, JORGE; NAVAS, CARLOS ARTURO; SARAIVA CAMARA, NIELS OLSEN; KOWALTOWSKI, ALICIA J.. Caloric Restriction Promotes Structural and Metabolic Changes in the Skin. CELL REPORTS, v. 20, n. 11, p. 2678-2692, SEP 12 2017. (10/51906-1, 14/17270-3, 12/02270-2, 13/04871-6, 14/16320-7, 13/07937-8)