CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Dentistry from Universidade Estadual Paulista Júlio de Mesquita Filho (2002), Master in Oral Rehabilitation from Universidade Estadual Paulista Júlio de Mesquita Filho (2005), PhD in Oral Rehabilitation from Universidade Estadual Paulista Júlio de Mesquita Filho (2009) and post-doc at the School of Dentistry, Araraquara, UNESP (2011) and Rutgers Health, School of Dental Medicine. He is currently an associate professor at the Universidade Estadual Paulista Júlio de Mesquita Filho and postdoc at Rutgers School of Dental Medicine. He was a visiting professor at the School of Pharmacy at the University of Ulster (2016) and at the School of Dentistry, University of California (UCLA, 2020). He has experience in the field of Dentistry, with emphasis on Dental Materials, acting mainly on the following topics: biofilms, photodynamic therapy, candida, candida albicans, candidiasis, removable prosthesis, microbiome, dental implants. (Source: Lattes Curriculum)
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Oral candidiasis (OC) is the main oral fungal infection and alternative treatments have been investigated, such as antimicrobial Photodynamic Therapy (aPDT) and Sonodynamic Therapy (SDT). Candida albicans (Ca) is the main microbial etiological factor for OC, but other Candida species have been isolated, such as C. tropicalis (Ct), which is the most pathogenic and prevalent species after C…
The ability of Candida albicans to switch its morphology from yeast to filaments, known as polymorphism, may bias the methods used in microbial quantification. Here, we compared the quantification methods [cell/mL, colony forming units (CFU)/mL, and the number of nuclei estimated by viability polymerase chain reaction (vPCR)] of three strains of C. albicans (one reference strain and two c…
Denture stomatitis (DS) is a common infection in denture wearers, especially women. This study evaluated the induction of DS using acrylic devices attached to the palate of rats combined with inoculation of Candida spp. Immunocompetent male and female rats received a carbohydrate-rich diet. Impressions were taken from the rats' palate to individually fabricate acrylic devices. Mono- and m…
The aim of this proposal is to start an international partnership by means of international visits for knowledge exchange, and strengthen international engagement in research activities. We are focused on the synthesis of nanosystems for light-controlled release of curcumin. Nowadays, the development of antimicrobial resistance is a world threat and a challenge for the health field, and n…
(Only some records are available in English at this moment)
Candida albicans is the main fungus pathogen that affects humans and has the ability to develop in different morphologies (yeasts, pseudo-hyphae and hyphae), a characteristic called polymorphism. This polymorphism and antifungal therapies compromise the quantification methods that demand and accuracy, such as research involving filamentous fungi. The aim of the study will be to compare th…
Curcumin (CUR) has been used as a photosensitizer (PS) in antimicrobial photodynamic therapy (aPDT) for inactivation of microorganisms. However, the use of organic solvents to solubilize CUR is a limitation for its clinical use. Taking this restriction into consideration, drug delivery systems such as polymeric micelles have been used to improve the solubility of CUR. Most studies of CUR …
Os objetivos desta pesquisa são: 1- comparar métodos não moleculares e molecular de quantificação de Candida albicans; 2- avaliar o efeito de inibidores de sistema de efluxo microbiano na inativação de biofilmes de C. albicans resistente a fluconazol; 3- desenvolver um sistema de micelas fotoativo de curcumina e avaliar sua ação na terapia fotodinâmica antimicrobiana (aPDT); 4- avaliar a …
(Only some records are available in English at this moment)
Peri-implantitis (PI) is an immune-mediated, inflammatory disease of the oral mucosa around dental implants, which serves as an excellent model to study the host- microbiome dynamic interactions. Interestingly, peri-implant microbiomes are under the constant pressure of biomaterial-derived microenvironmental challenges that arise from the in situ breakdown of the implant biomaterial in th…