Abstract
The aim of the present project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" da Fapesp - 2014 (AU)
Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Cleopatra da Silva Planeta in research grants and scholarships supported by FAPESP.
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The aim of the present project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" da Fapesp - 2014 (AU)
The aim of the present project is to describe the application plan of the School of Pharmaceutical Sciences for the grant related to the "Reserva Técnica Institucional" da Fapesp - 2013. (AU)
(Only some records are available in English at this moment)
The medial Prefrontal Cortex (mPFC) is a limbic structure involved in the expression of physiological and behavioral responses to conditioned aversive stimuli, including those evoked by Contextual Fear Conditioning (CFC). However, the local neurochemical mechanisms in the mPFC involved in controlling the responses to CRC are still poorly understood. In this sense, the presence of peptides…
Several evidences in the literature have demonstrated the deleterious effects that acute and chronic stress can trigger in individuals. The emergence of depression and anxiety disorder are possible consequences of these effects. The social defeat (SD) stress is an animal model that can be used to investigate the effects of acute and chronic stress on anxiety-related behavior in mice submi…
The medial prefrontal cortex (mPFC) is ivolved in the modulation of different behaviors, which include those associated with the use of ethanol and response to stressors. This brain region is predominantly composed of glutamatergic neurons and GABAergic interneurons, in addition to receiving dopaminergic afferents from the ventral tegmental area. Recently, it has been proposed that the mP…
(Only some records are available in English at this moment)
The medial prefrontal cortex - mPFC is a limbic structure that is involved in the expression of physiological and behavioral responses to conditioned aversive stimuli, including those triggered by conditioned fear. However, the local neurochemical mechanisms in the mPFC involved in the control of responses to the conditioned fear are still poorly understood. In this sense, it is described…
Post-traumatic stress disorder (PTSD) is shown to increase the sensitivity of glucocorticoid signaling through glucocorticoid receptor. Furthermore, is related to disfunction of brain structures associated to fear response. Homologous circuits such as infralimbic cortex (IL) to basolateral amygdala (BLA), produces extinction and reinstatement deficits in rodents. While the PTSD-related GR…
Rats submitted to the single prolonged stress (SPS) procedure demonstrate impaired fear extinction and increased anxiety, similar to those behavioral and physiological symptoms observed in posttraumatic stress disorder (PTSD) patients. The prefrontal cortex (PFC) plays a role in the modulation of emotional memory consolidation through its interactions with other brain regions like the amy…
(Only some records are available in English at this moment)
12 / 8 | Completed research grants |
25 / 17 | Completed scholarships in Brazil |
6 / 5 | Completed scholarships abroad |
43 / 30 | All research grants and scholarships |
Associated processes |