CV Lattes
ResearcherID
ORCID
Google Scholar Citations
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Farmácia Bioquímica from Universidade de São Paulo (1975), graduate at Farmácia from Universidade de São Paulo (1974), master's at Biochemistry from Universidade de São Paulo (1980) and PhD. at Biochemistry from Universidade de São Paulo (1985). Has experience in Biochemistry, focusing on Biochemistry, acting on the following subjects:, snake venoms of genus Bothrops and Crotalus, tabernaemontana catharinensis, tityus serrulatus and scorpion venom. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
The purification of active components from venoms with high purity and in relatively high amounts is a limiting factor for the success of this project, since these active molecules are the object of study of all the proposed tests, aiming at obtaining compounds with biotechnological potential. Prominence chromatography system is a modern equipment and meets all requirements for the isolat…
Snake venoms are complex mixtures of biological active compounds, among them, still little explored, the low molecular weight compounds, as the peptides, organic compounds and lipids. These molecules have diversified pharmacology activity and has been waking up a crescent scientific interesting about their anticancer potential. Although there are several peptides related with Bothrops gen…
The automatic sequencer of proteins/peptides is an equipment whose function is to identify the amino acids which comprise the primary structure of proteins and peptides. This identification occurs through the N-terminal region of the protein by Edman degradation and identification of PTH-amino acids. It is an essential equipment for laboratories working with identification and biochemical…
The equipment is a capillary electrophoresis platform for proteins and nucleic acids, and will be used for quantification and determination of the molecular weight of proteins (14kDa to 200 kDa), to determine the purity profile, glycosylation profile, and the purity and fragmentation of antibodies, as well as the separation and quantification of DNA and RNA. The advanced technology of thi…
(Only some records are available in English at this moment)
Arthropod venoms are composed by a wide range of compounds with a variety of pharmacological properties. These molecules have been studied and some successfully applied for anticancer therapy. Endoparasitoids use a pool of regulatory molecules in order to turn their hosts into a suitable environment for their offspring development. These regulatory molecules from parasitoids are still poo…
Leukemia is a very recurrent type of cancer characterized by the involvement of leukocytes. The currently recommended treatment for the disease consists of the use of chemotherapeutic agents that are highly aggressive to the patient, which makes evident the need to develop new, more effective and less toxic therapies. Snake venom is characterized by a complex chemical composition that inc…
Leukemia is a malignant disease of white blood cells, usually of unknown origin, whose main characteristic is the accumulation of abnormal young cells in the bone marrow, which replace normal blood cells. To evaluate new alternative therapies for the treatment of this disease, that affects thousands of individuals every year, this research project aims to evaluate the antitumor activity o…
Snake venoms are complex mixtures of biologically active compounds, among these, the peptides, still little explored. Shaped by evolutionary processes, these peptides are characterized by presenting diverse structures with a high degree of selectivity, what became them important candidates for models of the development of new drugs and biological tools. Therefore, the present study propos…
(Only some records are available in English at this moment)
Snakebites are considered a health problem in most tropical countries and Bothrops genus is major cause of accidents in Brazil. Bothrops moojeni belongs to the Viperidae family, popularly known as "caiçara" or "jararacão" and is found in the Midwest and Southeast of Brazil. The accident is characterized by proteolytic (or necrotizing), coagulant and hemorrhagic activities. The snake veno…
| 1 / 1 | Ongoing grants |
| 20 / 6 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 31 / 19 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 54 / 28 | All research grants and scholarships |
| Associated processes | |