CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade de São Paulo (2000), master's at Biochemistry from Universidade Estadual Paulista Júlio de Mesquita Filho (2003) and doctorate at Farmacologia from Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo (2006). Has experience in Pharmacology, focusing on Pharmacology, acting on the following subjects: fungos, purificação de enzimas, xilanases, resíduos agroindustriais and hipertensão arterial. (Source: Lattes Curriculum)
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Live-cell image visualization is an effective tool that empowers scientists to study living organisms instantly. Especially when used in conjunction with fluorescence microscopy, this technique enables the observation of cellular components with great sensitivity and precision. By illuminating the dynamics of different compounds and structures in living cells, it is possible to clarify th…
Preeclampsia (PE) is a specific syndrome of human pregnancy, being one of the main causes of maternal death worldwide. Half of patients with PE do not respond to current therapies, and despite this, its pathophysiology is not yet fully understood. It is known that endothelial dysfunction, inflammation and oxidative stress are fundamentally important in this process. Persistent inflammatio…
It is likely that the Endothelial Dysfunction (ED) found in Hypertensive Disorders of Pregnancy (HDP) are evoked by the actions of multiple factors and several pathways. Then the discovery and the understanding of these converging pathways that contribute to ED and poor outcome of pregnancy can addressing potential molecules with are modulated by different drugs. The use of omics tools, s…
Preeclampsia is the main cause of mortality and morbidity among pregnant women in Brazil and in several countries. The pathophysiology of this disease is complex and involves several processes. One of them is related to deficiency of the nitric oxide (NO). A possible cause of this deficiency could be the high expression of the enzyme arginase, which competes for the substrate (L-arginine)…
Myeloperoxidase is a proinflammatory enzyme found to be increased in patients with established preeclampsia but never investigated before the disease onset. Here we examined myeloperoxidase concentration and activity in plasma and urine samples from pregnant women who remained normotensive throughout pregnancy and those who developed preeclampsia in order to assess its potential to predic…
(Only some records are available in English at this moment)
Preeclampsia (PE) is a critical gestational condition that affects a large proportion of pregnancies worldwide and is responsible for thousands of maternal and fetal deaths annually. Hypertension and manifestations such as proteinuria and systemic inflammation are characteristic of the disease, resulting in persistent complications for mothers and babies. The pathophysiology of PE is rela…
Pre-eclampsia (PE) is a hypertensive syndrome that occurs during pregnancy and represents one of the main causes of maternal mortality in Brazil and worldwide. Although the pathophysiology of PE is not yet completely understood, it is known that failure of trophoblastic invasion plays a fundamental role, resulting in placental ischemia and subsequent hypoxia. These events are significant …
Preeclampsia (PE) is defined by the American College of Obstetricians and Gynecologists as a pregnancy syndrome associated with hypertension, typically diagnosed after 20 weeks of gestation and often near term. The pathophysiology of the disease can be presented in two stages. The first stage involves the failure in the remodeling of maternal uterine spiral arteries, resulting in placenta…
(Only some records are available in English at this moment)
It is likely that the Endothelial Dysfunction (ED) found in Hypertensive Disorders of Pregnancy are evoked by the actions of multiple factors and several pathways. Then the discovery and the understanding of these converging pathways that contribute to ED and pooroutcome of pregnancy can addressing potential molecules with are modulated by different drugs. The use of omics tools, such as …
Preeclampsia (PE) is a human gestational disorder, one of Brazil's leading causes of obstetric maternal death. Although its physiopathology hasn't been completely elucidated, PE is related to placental ischemia, once the release of substances resulting from inadequate perfusion in the maternal circulation can lead to systemic endothelial dysfunction. These substances can behave like infla…
Preeclampsia (PE) stands out as the main gestational hypertensive syndrome responsible for high rates of morbidity and mortality in Brazil and worldwide. The disease is characterized by hypertension (e140 / 90 mmHg), which in turn is often accompanied by proteinuria, in addition to dysfunction of target organs, such as kidneys and liver. The pathophysiology of PE is not yet fully elucidat…
(Only some records are available in English at this moment)
Preeclampsia (PE) is a specific syndrome of human pregnancy and the clinical parameters that define it are well understood. However, given the severity for the mother and fetus and the confirmation of the diagnosis only after the twentieth week of gestation, many studies have evaluated the use of biomarkers, such as the ratio between sFlt-1 (soluble vascular endothelial growth factor rece…
| 3 / 3 | Ongoing grants |
| 11 / 8 | Completed research grants |
| 8 / 8 | Ongoing scholarships in Brazil |
| 14 / 12 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 37 / 32 | All research grants and scholarships |
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