CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Medicina Veterinária e Zootecnia (FMVZ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Veterinary Medicine from the School of Veterinary Medicine and Animal Science - Unesp, Botucatu campus (1991), with a Residency in Large Animal Clinic (1992-1993) specializing in Veterinary Neurology. Holds a Master's degree (1997) and a Ph.D. (2002) in Veterinary Clinic from FMVZ-Unesp. Completed postdoctoral studies in Cell Therapy at the Veterinary Institute for Regenerative Cures - University of California, Davis - USA. Leader of a research group at CNPq and academic coordinator of the Interdisciplinary Studies in Cannabis League - NEICANN - Unesp. Associate professor of the Department of Veterinary Clinic and the Graduate Program in Veterinary Medicine (Capes rating 7) at the School of Veterinary Medicine and Animal Science - Unesp, Botucatu campus. Engaged in teaching, research, and extension activities in the areas of Veterinary Clinic, Veterinary Neurology, Cell-based Therapy, Regenerative Medicine, and Cannabis sativa L.. (Source: Lattes Curriculum)
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Inflammatory injuries of the central nervous system (CNS) are particularly disabling for both human and domestic animals. Multiple Sclerosis (MS) in humans and Meningoencephalomyelitis of Unknown Origin (MUO) in dogs are the most common neuroimmune diseases. The Experimental Autoimmune Encephalomyelitis (EAE) in mice, as animal model for MS, has contributed to the understanding of the pat…
Researches with mesenchymal stem cells (MSCs) and tissue engineering have shown that prospects will likely benefit the health of both humans and domestic animals, among them performance horses. The high differentiation potential of MSCs in different cell types, it's easy expansion in culture and the possibility of transplants have led to increased research into these cells. The therapeuti…
Peripheral nervous system (PNS) injuries are common clinical conditions in humans and animals, affecting the quality of life of affected patients. Equines are relevant as a translational model, as peripheral nerve injuries are common in the species, and the nerve size allows for more realistic data on nerve regeneration in humans. Although the PNS has regenerative capacity, mainly due to …
Research in regenerative medicine has advanced with the use of mesenchymal stem cells (MSCs). These cells are characterised by their fibroblast-like morphology, mesenchymal immunophenotype, self-renewal capacity, and differentiation potential into osteogenic, adipogenic, and chondrogenic lineages. MSCs can be isolated from various tissues, such as adipose tissue, and their therapeutic pot…
Cannabidiol (CBD), the main non-psychoactive component of Cannabis sativa, has shown promise due to its therapeutic potential as an alternative to traditional medications in various areas of veterinary medicine, especially in the treatment of inflammation, chronic pain, and neurological disorders in animals. However, there is a significant gap in knowledge regarding its safety and efficac…
(Only some records are available in English at this moment)
Horses with immune-mediated or autoimmune diseases have an exacerbated inflammatory response that is difficult to control, with a prognosis reserved, generating significant expenses with medications. The conventional treatment with the use of steroidal or non-steroidal anti-inflammatory drugs, has high potential to cause gastrointestinal and renal adverse effects. Asalternative treatment,…
The Endocannabinoid System constitutes a complex set of signaling pathways whose functions range from presynaptic neuronal inhibition to immunomodulation. The system's endogenous messengers are lipids synthesized on demand (anandamide and 2-arachidonoyl glycerol) that interact with G protein-coupled receptors (CB1 and CB2). CB1 receptors are found primarily in the central nervous system (…
Obesity is a growing disease in the human population and in the canine population. Data indicate that about 20% of dogs in industrialized countries are obese. The etiology of this disease is directly related to an energy imbalance, in which the animal obtains more energy than it actually needs, causing accumulation of it. The energetic excess is stored in the form of lipids in the adipose…
(Only some records are available in English at this moment)
Over the past decade, stem cell therapy has become a corner stone in translational and regenerative medicine for many diseases. However, brain and spinal cord diseases represent a challenge in stem cell based therapy. Stem cells therapies for CNS injury can be driven either with cell replacement by transplanted stem cells or by stimulation of endogenous CNS stem cells; and by the improvem…
Mesenchymal stem cells (MSCs) are a promising tool for treatment of a variety of injuries and disorders because of their secretion of numerous bioactive molecules leading to tissue regeneration. The central nervous system (CNS) has a limited capacity for regeneration. As such, MSCs are being evaluated as a cell therapy for a number of chronic degenerative and inflammatory neurological con…
| 1 / 0 | Ongoing grants |
| 3 / 2 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 10 / 8 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 22 / 18 | All research grants and scholarships |
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