Irma de Godoy

• Abstract

  Smoking is a chronic disease and the leading preventable cause of death worldwide; it is related to more than 50 diseases, including chronic obstructive pulmonary disease (COPD). COPD is defined as a preventable and treatable disease with systemic effects that can contribute to the severity of the patient. In addition to chronic inflammation, apoptosis, extracellular matrix degradation an…

  Genetic, transcriptomic, inflammatory and oxidative status alterations in smokers and in patients with chronic obstructive pulmonary disease, AP.R

• Abstract

  Evidence in the literature show that oxidative stress and systemic inflammation occur in smokers and in patients with mild/moderate chronic obstructive pulmonary disease (COPD). Comorbidities, malnutrition, decreased lean body mass, muscle dysfunction are prevalent and have adverse consequences on functional exercise capacity, general health and prognosis of patients with COPD. However, f…

  Association between oxidative stress, inflammation and systemic manifestations in smokers and patients with mild and moderate COPD, AP.R

• Abstract

  Cigarette smoking is the leading cause of preventable death worldwide. Approximately 50% of all smokers die from smoking-related diseases and about one-third of the adult population smokes. The main tobacco-related diseases are cardiovascular disease (CVD), cancer of various sites and chronic obstructive pulmonary disease (COPD). The overall impact of COPD is increasing and it is estimate…

  Electrocardiographic and echocardiographic study of patients with chronic obstructive pulmonary disease, AP.R

(Only some records are available in English at this moment)

• Abstract

  The staging of Chronic Obstructive Pulmonary Disease (COPD) has changed over the last 10 years with the introduction of new outcome markers. However mortality according to the different staging system is not established and has not been evaluated in patients with COPD who live in Brazil. Objectives: To compare the mortality of patients with COPD, in two years, classified according to the …

  Mortality of patients with chronic obstructive pulmonary disease (COPD) in the two year period: GOLD 2003 versus 2014, BP.IC

• Abstract

  Introduction: interventions for smoking cessation during pregnancy are highly effective in preserving life and reducing damage to health. The highest rates of smoking cessation in women occur in pregnancy; however, only one third maintain abstinence after childbirth. Prevention of relapse in this period is important and widely discussed in the literature. Due to the high prevalence of tob…

  Effects of brief smoking cessation intervention directed to pregnant women during pregnancy period and postpartum, BP.DR

• Abstract

  Studies show association of tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL6) and C-reactive protein (CRP) with systemic manifestations of COPD and greater mortality risk. However, there are no studies showing the evolution of these markers. In a previous study, 133 patients with mild to moderate COPD were followed and held the assessment of diagnostic and prognostic markers of…

  Follow-up study of inflammatory markers in COPD patients in a three years period, BP.DR