CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Instituto de Biociências (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Universidade de São Paulo (1984), master's at Genetics from Universidade de São Paulo (1988) and doctorate at Genetics from Universidade de São Paulo (1994). Has experience in Genetics, focusing on Human and Medical Genetics, acting on the following subjects: surdez hereditária, surdez não sindrômica, quilombos, genética de populações and surdez sindrômica. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| La edad de la leche |
| The age of milk |
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| News published in Agência FAPESP Newsletter about the researcher |
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The Human Genome Research Center (HGRC-CEPID I) was initiated in 2000 with the main goal of increasing our basic knowledge and diagnosis of prevalent genetic diseases in the Brazilian population. The HGRC concentrated largely on Mendelian disorders, mainly neuromuscular, craniofacial, and mental disability. The scope was expanded in 2005 by incorporating stem-cell research, both as a too…
Healthy aging and longevity are a growing topic of interest. They depend on the complex interplay between nuclear and mitochondrial DNA, the environment and the microbiota, that is, the whole set of bacteria living in the different parts of our body with their whole set of genes. Understanding this complex nature versus nurture balance is one of the greatest challenges in human genetics a…
(Only some records are available in English at this moment)
Essential Hypertension (EH) is a multifactorial condition characterized by chronic elevation of blood pressure (¿140/90 mmHg), with high global prevalence and significant impacts. Genomic studies have advanced the understanding of its genetic basis but still fail to explain its entire heritability, especially in admixed populations such as the Brazilian one. Investigating EH from a geneti…
Overweight and obesity (OWO) are growing concerns in the public health field due to their association with different mortality causes. Genomic researches have been focousing on European ancestry cohorts, therefore there is a significant gap regarding genetic variants that might increase susceptibility to OWO in non-white and mixed-race populations, such as the Brazilian population. In thi…
According whith the available archaeological evidence, the civiliization centers around the world have their antecedents in coastal populations with impressive signals of monumentality as an expression of territoriality and sedentary lifestyle. Despite the different trajectories, the evidence suggests that these societies were initially based on a predominantly marine subsistence, becomin…
There is consensus that the HLA genes (Human Leucocyte Antigen), which encode proteins essential for adaptive immune response, evolve under balancing selection regime - which increases the genetic diversity compared to the expected under neutrality. However, questions concerning the time scale of the action of natural selection and its effects on population differentiation remain controve…
The most frequent cause of recessive hearing loss are mutations in GJB2 gene (connexin26, Cx26). Among the individuals with hearing loss with mutations in this gene, 10% to 50% present a single recessive mutation in heterozygosis, indicating that haplo-insufficiency of GJB2 may interact with other types of mutations in the same gene, in the neighbor gene GJB6, or even in other genes. The …
(Only some records are available in English at this moment)
Overweight and obesity (OWO) are risk factors for noncommunicable diseases that are among the leading causes of death in the world. These are highly polygenic, complex phenotypes whose genetic architecture is being characterized. However, most genomic studies are focused on populations with European ancestry. Our knowledge about genetic variants with relevant effects in admixed and underr…
| 1 / 1 | Ongoing grants |
| 7 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 17 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 28 / 13 | All research grants and scholarships |
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