Abstract
Domestic dogs are the main urban reservoirs of Leishmania infantum, the causative agent of Visceral Leishmaniasis (VL) in the Americas. In VL-endemic regions, the number of human cases is associated with the rate of canine infection. In CanL, sick dogs mount an inefficient cellular immune response (Th1) to combat the parasite concomitantly with an increased humoral immune response (Th2). …