CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Farmácia Bioquímica from Universidade Estadual Paulista Júlio de Mesquita Filho (1992), master's at Farmacologia Ribeirão Preto from Universidade de São Paulo (1995), master's at Farmacologia Mestrado Sandwich from University of Iowa (1995) and ph.d. at Pharmacology from Universidade Federal de São Paulo (1999). Has experience in Physiology, focusing on Cardiovascular Physiology, acting on the following subjects: angiotensina ii, resposta pressora, pressão arterial, órgão subfornical and av3v. (Source: Lattes Curriculum)
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Obesity and hypertension are the leading cause of death in the world. Obesity and overweight contribute to elevated blood pressure in many patients with essential hypertension. Experimental and clinical studies indicate that visceral obesity induces hypertension by increasing renal sodium reabsorption through multiple mechanisms including activation of the sympathetic nervous system (SNS)…
(Only some records are available in English at this moment)
Overweight and obesity are major risk factors for many chronic diseases, including cardiovascular diseases such as hypertension. There is a high prevalence of obesity and hypertension in postmenopausal women. Women also ingest more sodium than men, correlating with higher blood pressure (BP) values. In this study, using an animal model, we will verify if obese female rats with free access…
During obesity, there is an increase in the renin-angiotensin system (RAS) activity. Thus, a greater RAS activation, and the consequent increased levels of peripheral angiotensin II (ANG II), can activate forebrain areas of the central nervous system (CNS) free of the blood brain barrier located in the lamina terminalis, and rich in ANG II receptors, such as the subfornical organ (SFO). W…
In recent decades obesity has become a worldwide epidemic. Excess adipose tissue favors the development of associated diseases such as high blood pressure and also causes changes in hydroelectrolytic balance, which may also affect blood pressure. Data from the literature show that obesity activates the renin-angiotensin system (RAS) and we have recently demonstrated that rats fed a high-f…
(Only some records are available in English at this moment)
Obesity is defined as the excessive accumulation of fat that causes damage to the health of the individual. In recent decades, some factors have been attributed to weight gain, such as increased intake of highly energetic foods that are high in fat and an increase in physical inactivity. High-fat diet induced-obesity leads to a greater activation of the renin-angiotensin system including …
Obesity is associated with the development of pathologies including cardiovascular diseases, hormonal and respiratory dysfunctions. Recently, studies have suggested that gestational obesity may also have an impact on the development of pathologies in offspring. The cardiorespiratory changes observed in the offspring promoted by maternal obesity, as well as the neural mechanisms involved, …
The nucleus of the solitary tract (NTS) is the primary synaptic site of different visceral afferents, including the baroreceptors. A functional cholinergic system has been described in the NTS. Microinjection of acetylcholine (ACh) or the muscarinic agonist carbachol into the intermediate NTS (iNTS) of anaesthetized or awake rats induces dose-dependent baroreflex-like hypotensive and brad…
(Only some records are available in English at this moment)
| 7 / 6 | Completed research grants |
| 19 / 9 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 30 / 19 | All research grants and scholarships |
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