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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Faculdade de Medicina (FMB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Dr. Elgui de Oliveira received a Biomedical Sciences degree from the Institute of Biosciences of Botucatu (1997) at the São Paulo State University "Júlio de Mesquita Filho" (UNESP). He earned a PhD in Pathology from the Botucatu Medical School (FMB; 2002), UNESP, and completed postdoctoral studies at Weill Cornell Medical College, USA (2008-2009). He currently holds a full-time position at UNESP, serving as a faculty member in the Department of Pathology at FMB since 2003 and as a researcher at the UNESP Institute of Biotechnology since 2015. His expertise is in Human Pathology, with an emphasis on Oncology and Molecular Pathology. His research focuses on cancer biology, viral carcinogenesis, and environmental carcinogenesis. He has undertaken short-term research fellowships at various international institutions, including: Children's Women's Hospital / University of British Columbia (Vancouver, BC, Canada; 2004); Texas Children's Hospital / Baylor College of Medicine (Houston, TX, USA; 2005); Hillman Cancer Center / University of Pittsburgh (Pittsburgh, PA, USA; 2006); Weill Medical College / Cornell University (New York, NY, USA; 2007; 2008-2009); and the Whitehead Institute / Massachusetts Institute of Technology (Cambridge, MA, USA; 2012). He is the Coordinator and Principal Investigator of the Viral Carcinogenesis and Cancer Biology Study Group (ViriCan - http://virican.net) since its foundation, in 2002. More information: ORCID: https://orcid.org/0000-0001-5562-9648; Google Scholar - http://goo.gl/wdGbi; FAPESP: http://goo.gl/DTTxT. (Source: Lattes Curriculum)
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The Epstein-Barr Virus (EBV) encodes viral microRNAs (miRs) that have been implicated in the pathogenesis of nasopharyngeal and gastric carcinomas, yet their potential roles in lymphomas remain to be fully elucidated. This study aimed to evaluate the impact of CRISPR/Cas9-mediated knockdown of EBV miRs BART-7 and BART-9 in EBV-positive Burkitt lymphoma cells Akata. As anticipated, the Aka…
EBV infection is implicated in the pathogenesis of proliferative disorders and various human cancers, notably the endemic form of Burkitt's Lymphoma and the undifferentiated variant of nasopharyngeal carcinoma. EBV was the first virus in which small non-coding RNAs (miRs) were found encoded in the viral genome. On the other hand, in the last two decades it has been verified that human end…
The Epstein-Barr virus (EBV) is a gammaherpesvirus associated with the development of different human cancers, notably the endemic Burkitt lymphoma and nasopharyngeal carcinoma, as well as a subset of cases of Hodgkin's lymphoma, gastric carcinoma, and some non-Hodgkin lymphomas, particularly in immunocompromised individuals. The carcinogenic potential of the virus is attributed to the ac…
(Only some records are available in English at this moment)
Cancers are a global health concern, with significant impacts in terms of morbidity and mortality, particularly in older adults. Population ageing and the high prevalence of unhealthy lifestyle habits have led to expectations of an increase in the incidence of cancers worldwide. Some human cancers are associated with infectious agents, particularly the diseases most prevalent in developin…
Based on data from the World Health Organization (WHO), approximately 2 million new cases of cancers related to microorganism infections are estimated worldwide. The majority of the adult population has latent Epstein-Barr virus (EBV) infection, which is recognized as potentially carcinogenic to humans. EBV is found in neoplastic cells of virtually all cases of the African endemic form of…
The Epstein-Barr virus (EBV) - formally human gammaherpesvirus 4 (HHV-4) - is a herpesvirus associated with the development of a variety of human malignancies, notably Burkitt lymphoma (BL) and nasopharyngeal carcinoma (NPC), but also subsets of cases for Hodgkin and non-Hodgkin lymphomas (particularly in immunocompromised patients) and gastric carcinomas. The viral genome is detected in …
(Only some records are available in English at this moment)
The Epstein-Barr virus (EBV), formally designated human herpesvirus 4 (HHV-4) - is a ubiquitous virus that causes lifelong latent infection in over 90% of the world's human adult population. EBV infection is regarded as carcinogenic to humans and associated with a variety of human cancers, especially endemic Burkitt Lymphoma (BL) and nasopharyngeal carcinomas (NPC). Following primary infe…
The Epstein-Barr virus (EBV) - formally human gammaherpesvirus 4 (HHV-4) - is a herpes-virus associated with the development of a variety of human malignancies, notably Burkitt lym-phoma (BL) and nasopharyngeal carcinoma (NPC), but also subsets of cases for Hodgkin and non-Hodgkin lymphomas (particularly in immunocompromised patients) and gastric carcino-mas. World Health Organization dat…
The Epstein-Barr virus (EBV) latently infects more than 90% of human adults. Viral infection is associated to the development of infectious mononucleosis, as well as some cancers, including Burkitt lymphoma, undifferentiated nasopharyngeal carcinoma, a subset of Hodgkin lymphomas, and lymphoproliferative disorders in immunocompromised hosts. Epithelial cells and B lymphocytes are the majo…