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SELECTION PROCESS OF TICK ANTIGENS AND ANTI-TICK ANTIGENIC COMPOSITION

Document type:Patente
Inventor(s): Isabel Kinney Ferreira de Miranda Santos; José Marcos Chaves Ribeiro; Beatriz Rossetti Ferreira; Cecília José Veríssimo; Lucinda Giampietro Brandao; Sandra Regina Costa Maruyama; Elen Anatriello; Gustavo Rocha Garcia; Daniela Dantas Moré; Jesus Gilberto Valenzuela
Applicant: Office Of Technology Transfer Of National Institutes Of Health ; Universidade de São Paulo (USP)
Deposit date: June 2016, 28
INPI register:
721558.0 - INPI Search
IPC: C12N15/12 C07K14/435 A61K39/00 A61P33/14 C12Q1/68
Abstract

The present invention relates to a method for selecting tick antigens, comprising the following steps: producing a tick transcriptome; synthetising the proteins; selecting the antigenic proteins; assessing the biological importance of the selected proteins; cloning and subcloning the DNA sequences relating to the selected proteins; synthetising antigens against ticks; and also, to antigenic compositions against ticks useful for mammals.


Grantee:João Santana da Silva
Principal Investigator:João Santana da Silva
Institution: Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP)
Support type: Regular Research Grants

FAPESP's process: 06/04149-5 - Immunoscreening of Rhipicephalus microplus tick genes using reverse immunology to reveal novel anti-tick vaccine antigens
Grantee:Beatriz Rossetti Ferreira
Principal Investigator:Beatriz Rossetti Ferreira
Institution: Universidade de São Paulo (USP). Escola de Enfermagem de Ribeirão Preto (EERP)
Support type: Regular Research Grants

Grantee:Isabel Kinney Ferreira de Miranda Santos
Principal Investigator:Isabel Kinney Ferreira de Miranda Santos
Institution: Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP)
Support type: Regular Research Grants