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METHOD FOR OBTAINING LIPID NANOSTRUCTURES, THUS OBTAINED LIPID NANOSTRUCTURES AND USE THEREOF

Document type:Patente
Inventor(s): Patrícia Bento da Silva; Regina Célia Galvão Frem; Adelino Vieira de Godoy Netto; Antonio Eduardo Mauro; Ana Maria da Costa Ferreira; Fernando Rogério Pavan; Clarice Queico Fujimura Leite; Marlus Chorilli
Applicant: Universidade Estadual Paulista (UNESP)
Deposit date: July 2016, 22
INPI register:
PCT/BR2016/050168 - INPI Search
IPC: A61K 47/48 A61K 9/51 C07F 1/08 A61P 31/06 A61K 31/4409 A61K 9/107
Abstract

The present invention relates to a method for obtaining lipid nanostructures comprising copper-isoniazid compounds. In addition, the present invention relates to the lipid nanostructures comprising copper-isoniazid compounds obtained by the present method, and to the use thereof to prepare medicinal drugs against mycobacteria in general. In a preferred embodiment, the invention relates to the use of the lipid nanostructures comprising copper-isoniazid compounds obtained by the present method, preferably MEB-I3 and MEB-I1, to prepare medicinal drugs for the treatment of active and latent tuberculosis, respectively.


FAPESP's process: 11/22488-0 - Discrete metallosupramolecules and metal organic frameworks (MOFs): synthesis, characterization and properties
Grantee:Regina Celia Galvao Frem
Principal Investigator:Regina Celia Galvao Frem
Institution: Universidade Estadual Paulista (UNESP). Campus de Araraquara. Instituto de Química (IQ)
Support type: Regular Research Grants