Ana Carolina Rodrigues

I have experience in crystallography data processing, focusing on serial crystallography of macromolecules. I did my master's degree in Physics at the Gleb Wataghin Institute of Physics (IFGW) of the University of Campinas (UNICAMP), in partnership with the National Synchrotron Light Laboratory (Sirius LNLS) of the National Center for Research in Energy and Materials (CNPEM) in Campinas, Brazil. In my master's degree, I developed an automatic serial crystallography data processing routine for the Sirius Manacá line. The developed routine aims to adapt the line's users to software packages developed for the serial crystallography technique, such as CrystFEL. I did my PhD in Physics at the University of Hamburg, Germany, in collaboration with the Deutsches Elektronen-Synchrotron (DESY) Synchrotron. In my PhD, I developed the beam sweeping serial crystallography for MHz XFELs. Instead of moving the micropatterned silicon chip, a rotating silicon mirror aligned with the X-ray beam scans the samples vertically. This approach scans the crystals by reflecting each pulse in the train at a slightly different angle. With the beam sweeping serial crystallography, we aim to enable high-throughput room-temperature pharmaceutical screening at XFELs, achieving data collection times comparable to conventional X-ray cryocrystallography experiments. (Fonte: Currículo Lattes)