| Texto completo | |
| Autor(es): Mostrar menos - |
de Araujo, Gabriela Ribeiro
;
Morais-Perdigao, Ana Luisa
;
Bardalez Lopez de Caceres, Cinthia Veronica
;
Lopes, Marcio Ajudarte
;
Manuel Aguirre-Urizar, Jose
;
Carlos, Roman
;
Jose Roman Tager, Elena Maria
;
van Heerden, Willie F. P.
;
Robinson, Liam
;
Rebelo Pontes, Helder Antonio
;
Benevenuto de Andrade, Bruno Augusto
;
Soares, Ciro Dantas
;
Gomez, Ricardo Santiago
;
Fonseca, Felipe Paiva
Número total de Autores: 14
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Head and Neck Pathology; v. N/A, p. 11-pg., 2022-09-27. |
| Resumo | |
Background Lymphomas affecting the sublingual glands are extremely rare and very few case reports are currently available. Therefore, the aim of the current study is to describe the clinicopathological features of a series of lymphomas involving the sublingual glands. Methods Cases diagnosed in four pathology services were assessed and the formalin-fixed paraffin-embedded tissue blocks were retrieved for diagnosis confirmation. Clinical data were obtained from patients' medical files. Results We obtained seven cases of lymphomas in the sublingual glands, representing two follicular lymphomas, two diffuse large B cell lymphomas not otherwise specified (DLBCL NOS), two extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphomas) and one mantle cell lymphoma (MCL). In all cases the tumor cells infiltrated the glandular parenchyma, although in two of them the neoplastic cells were located more superficially and permeated the glandular acini and ducts. Clinically, the tumors presented as asymptomatic nodules and two patients (affected by DLBCL NOS and MCL) died, while the other five patients remained alive at last follow-up. Conclusion Lymphomas affecting the sublingual glands are usually of the mature B cell lineage, often represent low-grade subtypes and may clinically resemble other more common lesions in the floor of the mouth like salivary gland tumors. (AU) | |
| Processo FAPESP: | 17/14880-3 - Análise clinicopatológica e imunoistoquímica das hiperplasias linfoides foliculares e dos linfomas da cavidade oral |
| Beneficiário: | Oslei Paes de Almeida |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |