A review of hybrid enzymatic-chemical treatment for wastewater containing antiepileptic drugs

Autor(es)

Klanovicz, Natalia ; Camargo, Aline Frumi ; Ramos, Bruno ; Michelon, William ; Treichel, Helen ; Teixeira, Antonio Carlos Silva Costa

• Tipo de documento: Artigo Científico
• Fonte: Environmental Science and Pollution Research; v. 30, n. 27, p. 25-pg., 2023-05-15.

Resumo

Epilepsy is one of the most common neurological diseases worldwide and requires treatment with antiepileptic drugs for many years or for life. This fact leads to the need for constant production and use of these compounds, placing them among the four pharmaceutical classes most found in wastewater. Even at low concentrations, antiepileptics pose risks to human and environmental health and are considered organic contaminants of emerging concern. Conventional treatments have shown low removal of these drugs, requiring advanced and innovative approaches. In this context, this review covers the results and perspectives on (1) consumption and occurrence of antiepileptics in water, (2) toxicological effects in aquatic ecosystems, (3) enzymatic and advanced oxidation processes for degrading antiepileptics drugs from a molecular point of view (biochemical and chemical phenomena), (4) improvements in treatment efficiency by hybridization, and (5) technical aspects of the enzymatic-AOP reactors. (AU)

• Processo FAPESP: 21/08815-0 - Desenvolvimento de sistema híbrido combinando processo oxidativo avançado e biocatálise enzimática para degradação de drogas antiepiléticas em reator de escoamento contínuo
• Beneficiário: Natalia Klanovicz
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto