| Texto completo | |
| Autor(es): |
Caperuto, E. C.
;
dos Santos, R. V. T.
;
Mello, M. T.
;
Costa Rosa, L. F. B. P.
Número total de Autores: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Clinical and experimental pharmacology & physiology; v. 36, n. 2, p. 3-pg., 2009-02-01. |
| Resumo | |
Serotonin is a neurotransmitter that modulates several functions, such as food intake, energy expenditure, motor activity, mood and sleep. Acute exhaustive endurance exercise increases the synthesis, concentration and metabolism of serotonin in the brain. This phenomenon could be responsible for central fatigue after prolonged and exhaustive exercise. However, the effect of chronic exhaustive training on serotonin is not known. The present study was conducted to examine the effect of exhaustive endurance training on performance and serotonin concentrations in the hypothalamus of trained rats. Rats were divided into three groups: sedentary rats (SED), moderately trained rats (MOD) and exhaustively trained rats (EXT), with an increase of 200% in the load carried during the final week of training. Hypothalamic serotonin concentrations were similar between the SED and MOD groups, but were higher in the EXT group (P < 0.05). Performance was lower in the EXT group compared with the MOD group (P < 0.05). Thus, the present study demonstrates that exhaustive training increases serotonin concentrations in the hypothalamus, together with decreased endurance performance after inadequate recovery time. However, the mechanism underlying these changes remains unknown. (AU) | |
| Processo FAPESP: | 01/13766-4 - Os efeitos do treinamento moderado sobre o metabolismo muscular de glutamina e seu papel na manutenção da glutaminemia |
| Beneficiário: | Ronaldo Vagner Thomatieli dos Santos |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado Direto |