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Entree


Translational Control during Mammalian Neocortex Development and Postembryonic Neuronal Function

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Autor(es):
Martins Oliveira, Natassia Cristina ; Lins, Erico Moreto ; Massirer, Katlin Brauer ; Bengtson, Mario Henrique
Número total de Autores: 4
Tipo de documento: Artigo Científico
Fonte: SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY; v. 114, p. 11-pg., 2021-05-20.
Resumo

The control of mRNA translation has key roles in the regulation of gene expression and biological processes such as mammalian cellular differentiation and identity. Methodological advances in the last decade have resulted in considerable progress towards understanding how translational control contributes to the regulation of diverse biological phenomena. In this review, we discuss recent findings in the involvement of translational control in the mammalian neocortex development and neuronal biology. We focus on regulatory mechanisms that modulate translational efficiency during neural stem cells self-renewal and differentiation, as well as in neuronalrelated processes such as synapse, plasticity, and memory. (AU)

Processo FAPESP: 15/21433-8 - Identificação de vias moleculares reguladas traducionalmente na diferenciação neuronal
Beneficiário:Érico Luiz Moreto Lins
Modalidade de apoio: Bolsas no Brasil - Doutorado Direto