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Advances in Metallic-Based Localized Surface Plasmon Sensors for Enhanced Tropical Disease Detection: A Comprehensive Review

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Autor(es):
Farooq, Sajid ; Zezell, Denise Maria
Número total de Autores: 2
Tipo de documento: Artigo Científico
Fonte: Plasmonics; v. 19, n. 4, p. 22-pg., 2023-11-21.
Resumo

Tropical diseases present significant challenges to global health, particularly in resource-limited regions. Early and accurate detection of these diseases is vital for effective management and control. In recent years, metallic-based LSPR sensors have emerged as promising diagnostic tools for sensitive and rapid detection of tropical diseases. This comprehensive review aims to provide an in-depth analysis of the current state of research on metallic-based LSPR sensors for the detection of various tropical diseases. In this study, we focused on the connection between neglected tropical diseases (NTDs) and its risk using metallic-based LSPR sensors to identify potential inflammatory biomarkers. We conducted a literature search using PubMed, Web of Science, and Google Scholar. Only published materials written in English were considered, resulting in the identification of similar to 220 articles. After a comprehensive evaluation, we selected 35 relevant ones. Our analysis revealed 35 links to neglected tropical diseases, providing valuable insights into their relationship using metallic-based LSPR sensors. Moreover, we explore the potential of metallic-based LSPR sensors in point-of-care testing and their integration with emerging technologies such as microfluidics and smartphone-based diagnostics. This review underscores the need for continued research efforts to develop affordable, sensitive, and user-friendly metallic-based LSPR sensors for early detection and surveillance of tropical diseases. (AU)

Processo FAPESP: 21/00633-0 - Processamento e análise de sinais hiperespectrais aplicados ao diagnóstico histopatológico
Beneficiário:Luciano Bachmann
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 17/50332-0 - Capacitação científica, tecnológica e em infraestrutura em radiofármacos, radiações e empreendedorismo a serviço da saúde (PDIp)
Beneficiário:Marcelo Linardi
Modalidade de apoio: Auxílio à Pesquisa - Programa Modernização de Institutos Estaduais de Pesquisa