| Texto completo | |
| Autor(es): |
Souza, Shellyda G. G.
;
Silva-Neto, Habdias A.
;
Rocha, Danielly S.
;
de Siervo, Abner
;
Paixao, Thiago R. L. C.
;
Coltro, Wendell K. T.
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | ANALYSIS & SENSING; v. 4, n. 6, p. 9-pg., 2024-08-09. |
| Resumo | |
Here, we describe for the first time the fabrication of laser-induced graphene (LIG) electrodes on a hybrid substrate composed of sandpaper and polyester. As a proof of concept, the proposed device was used as a voltammetric sensor for tadalafil (TAD) quantification in authentic tablet samples. The electrochemical TAD sensing based on differential pulse voltammetry (DPV) revealed a linear behavior in the concentration range from 25 to 250 mu mol L-1(R-2=0.99), a limit of detection of similar to 9.6 mu mol L-1, sensitivity of similar to 0.0048 mu A(mu mol L-1)(-1) and acceptable reproducibility values (RSD <= 5.8 %). The DPV responses involving the standard addition method in pharmaceutical samples presented recovery results of TAD ranging from 93 to 108 %. Also, the proposed analytical method offered a suitable green analytical chemistry profile. We successfully demonstrated the fabrication of graphene-like sites and nanoparticles composed of alumina upon a hybrid substrate. (AU) | |
| Processo FAPESP: | 18/08782-1 - Sensores químicos miniaturizados e integrados: novas plataformas de fabricação para aplicações biológicas, clínicas e ambientais |
| Beneficiário: | Mauro Bertotti |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |