| Texto completo | |
| Autor(es): |
Avilez, Leonardo A. C.
;
Bresciani, Antonio E.
;
Ferreira, Newton L.
;
Nascimento, Claudio A. O.
;
Alves, Rita M. B.
Número total de Autores: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR; v. N/A, p. 17-pg., 2024-12-18. |
| Resumo | |
1,3-Propanediol (1,3-PDO) and lactic acid (LA) are valuable chemical products that can be used as monomers for synthesizing important polymers such as polytrimethylene terephthalate and poly(lactic acid), respectively. In this study, a new integrated process for the production of 1,3-PDO and LA from renewable feedstocks is proposed and analyzed using modeling and simulation tools. Limosilactobacillus reuteri was selected for this application due to its capability to co-ferment both glycerol and glucose, resulting in the production of 1,3-PDO, LA, and other byproducts. A conceptual process was developed and simulated using Aspen Plus software, focusing on the bioreactor, multistage evaporation, and vacuum distillation for separation. The bioreactor was designed using a kinetic model that had been developed previously, which was validated with experimental data. A technoeconomic and environmental analysis was conducted, along with a multi-criteria analysis using the GREENSCOPE methodology. The proposed process was compared with a study from the literature that reproduced metrics of a commercial 1,3-PDO production process, providing a benchmark for evaluation. The results of the economic assessment, particularly in the Brazilian market, estimate the minimal selling prices at US$6.70/kg for 1,3-PDO and US$5.49/kg for LA. Overall, the proposed process presents a potential technical solution for integrated LA and 1,3-PDO production; however, further studies should focus on increasing L. reuteri tolerance to higher substrate concentrations and developing low-cost culture media to ensure process sustainability. (AU) | |
| Processo FAPESP: | 22/09848-1 - Avaliação do processo de produção de 1,3-propanodiol por rota biotecnológica |
| Beneficiário: | Leonardo Antonio Cáceres Avilez |
| Modalidade de apoio: | Bolsas no Brasil - Programa Capacitação - Treinamento Técnico |
| Processo FAPESP: | 19/27111-3 - Estudos de tecnologias para o aumento da competitividade de plantas industriais de biodiesel e glicerol no contexto de uma biorrefinaria |
| Beneficiário: | Claudio Augusto Oller do Nascimento |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |