Effect of a lifestyle intervention among pregnant women with overweight on neonatal adiposity: A randomized controlled clinical trial

Autor(es)

Baroni, Naiara Franco ; Carvalho, Mariana Rinaldi ; Santos, Izabela da Silva ; Chaves, Ana Vitoria Lanzoni ; Miranda, Daniela Elias Goulart de Andrade ; Crivellenti, Livia Castro ; Sartorelli, Daniela Saes

• Tipo de documento: Artigo Científico
• Fonte: EARLY HUMAN DEVELOPMENT; v. 194, p. 8-pg., 2024-05-21.

Resumo

Background: The excess neonatal adiposity is considered a risk factor for the development of childhood obesity and the birth weight is a marker of health throughout life. Aims: To evaluate the effect of a lifestyle intervention conducted among pregnant women with overweight on neonatal adiposity and birth weight. Methods: A total of 350 pregnant women were recruited and randomly allocated into the control (CG) and intervention (IG) groups. Pregnant women in the IG were invited to participate in three nutritional counselling sessions based on encouraging the consumption of unprocessed and minimally processed foods, rather than ultra- processed foods, following the NOVA food classification system, which categorizes foods according to the extent and purpose of industrial processing, and the regular practice of physical activity. Neonatal adiposity was estimated using a previously validated anthropometric model. Adjusted linear regression models were used to measure the effect. Results: Adopting the modified intention-to-treat principle, data from 256 neonates were analyzed for birth weight, and data from 163 for body composition estimation. The treatment had no effect on the proportion of fat mass [(3 0.52 (95 % CI-1.03, 2.06); p = .51], fat-free mass [(3-0.50 (95 % CI-2.45, 1.45); p = .61] or birth weight [(3 53.23 (95 % CI-87.19, 193.64); p = .46]. Conclusions: In the present study, the lifestyle counselling used had no effect on neonatal adiposity or birth weight. Future studies should investigate the effect of more intensive interventions. (AU)

• Processo FAPESP: 17/15386-2 - Estudo de intervenção nutricional em gestantes com sobrepeso atendidas em Unidades Básicas de Saúde: um ensaio clínico aleatorizado controlado.
• Beneficiário: Daniela Saes Sartorelli
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/18980-2 - Adesão às metas de uma intervenção no estilo de vida entre gestantes com sobrepeso e seu efeito em desfechos perinatais
• Beneficiário: Lívia Castro Crivellenti
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 21/06486-9 - Impacto de uma intervenção nutricional em gestantes com sobrepeso sobre o crescimento e desenvolvimento infantil aos seis meses
• Beneficiário: Izabela da Silva Santos
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 21/06586-3 - Relação entre as características paternas e a antropometria da criança do nascimento ao primeiro ano de vida em um ensaio clínico de intervenção nutricional
• Beneficiário: Mariana Rinaldi Carvalho
• Modalidade de apoio: Bolsas no Brasil - Doutorado