| Texto completo | |
| Autor(es): |
Pavoni, Juliana Fernandes
;
Lizar, Jessica Caroline
;
Borges, Leandro Frederiche
;
Nicolucci, Patricia
;
Krutman, Yanai
;
Baffa, Oswaldo
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | GELS; v. 11, n. 5, p. 13-pg., 2025-04-30. |
| Resumo | |
Postmastectomy radiation therapy (PMRT) is an adjuvant treatment for breast cancer. Some mastectomized women undergoing PMRT can have breast reconstruction with expander implant reconstruction. However, the expander implant contains a magnetic metal port for its inflation, and in patients with a high risk of recurrence, the PMRT is performed before the expander replacement. The difficulties in radiation treatment near high-Z metals are mainly due to dose alterations around them. Therefore, this study proposes using a realistic breast phantom and gel dosimetry to investigate the effects of the metallic parts of the expandable prosthesis on the 3D delivery of the treatment. A conformal radiation treatment was planned and delivered to the gel phantom with the metal port. MAGIC-f gel was used with magnetic resonance imaging for dose assessment. The treatment plan dose distribution was compared to the measured dose distribution by gamma analysis (3%/3 mm/15% threshold). A significant gamma fail region was found near the metal port, corresponding to a dose reduction of approximately 5%. This underdose is within the tolerance threshold for dose heterogeneity established by the International Commission on Radiation Units (ICRU), but should be considered when treating these patients. (AU) | |
| Processo FAPESP: | 13/07699-0 - Centro de Pesquisa, Inovação e Difusão em Neuromatemática - NeuroMat |
| Beneficiário: | Oswaldo Baffa Filho |
| Modalidade de apoio: | Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs |
| Processo FAPESP: | 18/05982-0 - P&D&I em metrologia das radiações na área da saúde |
| Beneficiário: | Linda Viola Ehlin Caldas |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |
| Processo FAPESP: | 21/02254-6 - Aplicações de ferramentas de aprendizado de máquina em radioterapia |
| Beneficiário: | Juliana Fernandes Pavoni |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |