| Texto completo | |
| Autor(es): |
Schimenes, Bianca Camilo
;
Moreira, Gustavo A.
;
Alvarenga, Tathiana A.
;
Tufik, Sergio
;
Andersen, Monica Levy
Número total de Autores: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | BIOESSAYS; v. 48, n. 1, p. 7-pg., 2025-12-16. |
| Resumo | |
We propose a novel hypothesis that artificial food colors (AFCs) may act as sleep disruptors in children by interfering with neurochemical pathways involved in circadian regulation and behavioral stability. Although widely used in ultra-processed foods (UPFs) to enhance visual appeal, especially targeting children, emerging evidence suggests that frequent exposure to AFCs is linked to behavioral disturbances such as hyperactivity, irritability, and attention deficits, as well as sleep-related problems. Recent updates from the Food and Drug Administration (FDA) highlight growing regulatory concern about the health risks of petroleum-based colorants in pediatric populations. Despite these concerns, the current body of knowledge on the specific mechanisms through which artificial colorants may impact sleep remains limited and superficial. This paper proposes that AFCs may negatively affect sleep quality through disruptions in neurophysiological signaling, and it calls for rigorous investigation via double-blind, placebo-controlled, cross-over clinical trials, which may contribute to a better understanding of the neurobehavioral effects of AFCs and provide a scientific basis for future regulatory decisions and public health strategies. (AU) | |
| Processo FAPESP: | 20/13467-8 - Relação da apneia obstrutiva do sono e suas comorbidades com a microbiota intestinal: interface com sexualidade e função reprodutiva |
| Beneficiário: | Monica Levy Andersen |
| Modalidade de apoio: | Auxílio à Pesquisa - Temático |