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Topographical orientation assessment in a virtual reality environment in patients with mild cognitive impairment

Grant number: 16/04984-3
Support type:Research Grants - eScience Program - Regular Program Grants
Duration: October 01, 2016 - September 30, 2018
Field of knowledge:Health Sciences - Medicine
Principal Investigator:Sonia Maria Dozzi Brucki
Home Institution: Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo, SP, Brazil


Topographical orientation is a cognitive domain usually impaired in early manifestations of Alzheimer's Disease. Some studies have suggested that topographical disorientation can also be found in Mild cognitive impairment patients and is predictive symptom of progression to Alzheimer's Disease, which makes its assessment of high importance. Lack of standard neuropsychological tests for topographical orientation and the need to assess it in a more ecological way supports the development of new and more realistic forms of assessment, such as virtual reality tasks. This study provides two virtual reality tasks of topographical orientation assessment in mild cognitive impairment patients and their performance in comparison with normal elderly participants. (AU)