USY-zeolite catalyzed synthesis of 1,4-dihydropyridines under microwave irradiation: structure and recycling of the catalyst

Autor(es)

Alponti, Leonardo H. R. ^[1] ; Picinini, Monize ^[2] ; Urquieta-Gonzalez, Ernesto A. ^[2] ; Correa, Arlene G. ^[1]

Afiliação do(s) autor(es)

^[1] Ctr Excellence Res Sustainable Chem, Dept Chem, Sao Carlos, SP - Brazil

^[2] Univ Fed Sao Carlos, Dept Chem Engn, BR-13565905 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Molecular Structure; v. 1227, MAR 5 2021.
• Citações Web of Science: 0

Resumo

The Hantzsch three-component reaction is the best-known multicomponent reaction, affording dihydropyridines which have been employed therapeutically and also as visible-light photoredox catalysts. In this work we report the application of an ultra-stable (US) Y zeolite as a promising green catalyst in the synthesis of a series of 1,4-dihydropyridines under microwave irradiation. Using the optimized reaction conditions, 21 compounds were prepared in 64-96% isolated yields. The recovery and recycle of the USY zeolite are also reported as well as its fully characterization. (C) 2020 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
• Beneficiário: Arlene Gonçalves Corrêa
• Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia
• Processo FAPESP: 18/12367-0 - Síntese de nanocatalisadores oriundos da biomassa e emprego em reações multicomponentes
• Beneficiário: Leonardo Henrique Rondina Alponti
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 13/07600-3 - CIBFar - Centro de Inovação em Biodiversidade e Fármacos
• Beneficiário: Glaucius Oliva
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs