Hybrid encapsulation structures based on beta-carotene-loaded nanoliposomes within electrospun fibers

Autor(es)

de Freitas Zompero, Rafael Henrique ^[1] ; Lopez-Rubio, Amparo ^[2] ; de Pinho, Samantha Cristina ^[3] ; Lagaron, Jose Maria ^{[1, 3, 2]} ; de la Torre, Lucimara Gaziola ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Sch Chem Engn, UNICAMP, BR-13083970 Campinas, SP - Brazil

^[2] IATA, Novel Mat & Nanotechnol Grp, Inst Agrochem & Food Technol, Valencia 46980 - Spain

^[3] Univ Sao Paulo, Sch Anim Sci & Food Engn, Dept Food Engn, Pirassununga, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: COLLOIDS AND SURFACES B-BIOINTERFACES; v. 134, p. 475-482, OCT 1 2015.
• Citações Web of Science: 27

Resumo

Hybrid encapsulation structures based on beta-carotene-loaded nanoliposomes incorporated within the polymeric ultrathin fibers produced through electrospinning were developed to improve the photostability of the antioxidant. These novel materials were intended to incorporate beta-carotene into water-based food formulations, overcoming the existing limitations associated with its hydrophobic character. Initially, both empty and antioxidant-loaded nanoliposomes were developed and incorporated into polyvinyl alcohol (PVOH) and polyethylene oxide (PEO) solutions. The changes in the solution properties were evaluated to determine their effects on the electrospinning processing. The mixed polymer solutions were subsequently electrospun to produce hybrid nanoliposome-loaded ultrathin fibers. FTIR analysis confirmed the presence of phospholipid molecules inside the electrospun fibers. These ultrathin fibers were evaluated regarding their morphology, diameter, internal beta-carotene distribution and stability against UV irradiation. Liposomal release studies from the electrospun fibers were also undertaken, confirming the presence of the liposomal structures after dissolving the electrospun fibers in water. (C) 2015 Published by Elsevier B.V. (AU)

• Processo FAPESP: 13/05868-9 - Sistemas microfluídicos para a produção de nanopartículas multifuncionais destinadas à terapia gênica
• Beneficiário: Lucimara Gaziola de la Torre
• Modalidade de apoio: Auxílio à Pesquisa - Regular