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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

HIGH LEVELS OF BISPHENOL A AND BISPHENOL S IN BRAZILIAN THERMAL PAPER RECEIPTS AND ESTIMATION OF DAILY EXPOSURE

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Autor(es):
Rocha, Bruno Alves [1] ; Azevedo, Lara Ferreira [1] ; Gallimberti, Matheus [1] ; Campiglia, Andres Dobal [2] ; Barbosa, Jr., Fernando [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Fac Ciencias Farmaceat Ribeirao Preto, Lab Toxicol & Essencialidade Metais, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Univ Cent Florida, Dept Chem, Orlando, FL 32816 - USA
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES; v. 78, n. 18, p. 1181-1188, SEP 17 2015.
Citações Web of Science: 27
Resumo

Bisphenol A (BPA) is an endocrine and metabolic disruptor commonly employed as a color developer in thermal papers. Consequently, BPA derived from thermal papers has been considered an important source of exposure for humans, since this chemical may migrate from paper to skin upon contact. Further, due to recent restrictions on BPA use in some countries, it has been replaced by a new analogue, bisphenol S (BPS). The aim of the present study was to determine levels of BPA and BPS in 190 different thermal receipts, randomly collected from different locations in SAo Paulo State, Brazil, including receipts from supermarkets, general and fast-food restaurants, gas stations, bus and airplane tickets, and credit card and bank accounts. BPA and/or BPS were detected in 98% of samples at concentrations ranging from below the quantification limit to 4.3% (mg/100 mg paper). The obtained values were higher than amounts previously reported in other countries. The estimated daily intake through dermal absorption from handling of thermal receipt papers was estimated on the basis of concentrations and frequencies of handling of papers by humans in both the general population and occupationally exposed individuals. Fifth percentile, median, and 95th percentile daily intakes by the general population were 0.44, 1.42, and 2 g/d, respectively, whereas the corresponding values for occupationally exposed population are 21.8, 71 and 101 g/d. The potential adverse consequences of elevated occupational exposure are currently being examined. (AU)

Processo FAPESP: 13/23710-3 - Uso da espectroscopia Shpol'skii e LC-MS/MS para a determinação do bisfenol A e análogos em amostras de urina e avaliação da exposição em crianças residentes no estado de São Paulo
Beneficiário:Bruno Alves Rocha
Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado