Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Direct Electrochemical Detection of Estriol in Serum by Polymer Brushes Reinforced with Carbon Nanotubes

Texto completo
Autor(es):
Recco, Lucas ; Crulhas, Bruno P. ; Basso, Caroline R. ; Castro, Gustavo R. ; Pedrosa, Valber A.
Número total de Autores: 5
Tipo de documento: Artigo Científico
Fonte: ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY; v. 5, n. 8, p. M3041-M3044, 2016.
Citações Web of Science: 0
Resumo

The aim of this study was the development a simple and sensitive sensor for estriol detection in serum based on the combination of multiwalled carbon nanotubes with polymer brushes that provides a nanocomposite with high electrochemical response. Scanning electron microscopy was applied for characterization of the surface morphology of the modified electrodes and cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy were used to investigate the electrochemical properties of the proposed electrode. Linearity between oxidation peak current and estriol concentration was obtained ranging from 2.0 x 10(-6) M to 15 x 10(-6) M with a detection limit of 90 nM and sensitivity was calculated to be 0.15 mu A/mu M. The polymer reinforced carbon nanotube displayed high selectivity, good stability and reproducibility, making it suitable for the routine analysis of estriol in clinical use. (C) 2016 The Electrochemical Society. All rights reserved. (AU)

Processo FAPESP: 14/05653-5 - Desenvolvimento de um biossensor integrado para monitoramento do metabolismo celular
Beneficiário:Valber de Albuquerque Pedrosa
Modalidade de apoio: Auxílio à Pesquisa - Regular