ULTRASOUND ELASTOGRAPHY ASSESSMENT OF THE MEDIAN NERVE IN LEPROSY PATIENTS

Autor(es)

Nogueira-Barbosa, Marcello H. ; Lugao, Helena B. ; Gregio-Junior, Everaldo ; Crema, Michel D. ; Kobayashi, Mariana T. T. ; Frade, Marco A. C. ; Pavan, Theo Z. ; Carneiro, Antonio A. O.

• Tipo de documento: Artigo Científico
• Fonte: MUSCLE & NERVE; v. 56, n. 3, p. 393-398, SEP 2017.
• Citações Web of Science: 2

Resumo

Introduction: We sought to compare median nerve elasticity between leprosy patients (LPs) and healthy volunteers (HVs) using ultrasound elastography (UE). Methods: Two radiologists independently measured the strain ratio of the median nerve/flexor digitorum superficialis muscle (MN/FDSM) of 18 LP and 18 HV using real-time freehand UE. Statistical analysis included intra-class correlation coefficients (ICC) and MannWhitney test. Results: The MN/FDSM strain ratios of the LP and HV were 2.66 +/- 1.30 and 3.52 +/- 0.93, respectively (P < 0.05). We observed a significantly lower MN/FDSM strain ratio in LP with reactions (types 1 and 2 cutaneous reactions associated with or without neuritis) (2.30 +/- 0.91) compared with LP without reactions (3.60 +/- 1.70). We found no significant differences between HV and LP without reactions. The intra-and inter-observer ICCs were 0.50 (95% confidence interval {[}CI], 0.11-0.72) and 0.34 (95% CI, 0.28-0.52), respectively. Conclusions: MN/FDSM strain ratios were significantly lower in LP with reactions. UE may be useful for nerve elasticity evaluation in leprosy. (AU)

• Processo FAPESP: 13/18854-6 - Imagens fotoacústicas e ultrassônicas para caracterização de tecidos viscoelásticos
• Beneficiário: Theo Zeferino Pavan
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores