Perinodal fibrosis developed after ultrasonography-guided core-needle biopsy of a contrast-enhanced ultrasound-detected sentinel axillary node interferes with subsequent surgical sentinel node dissection

Autor(es)

Serquiz, Nicoli ^[1] ; Moro, Luciano ^[2] ; Menossi, Carlos A. ^[1] ; Almeida, Natalie R. ^[1] ; Baccarin, Gabrielle ^[1] ; de Paiva Silva, Geisilene R. ^[1] ; Shinzato, Julia Y. ^[1] ; Derchain, Sophie ^[1] ; Jales, Rodrigo M. ^[1]

Afiliação do(s) autor(es)

^[1] State Univ Campinas Unicamp, Fac Med Sci, Dept Obstet & Gynecol, Imaging Sect, POB 6111, BR-13083970 Campinas, SP - Brazil

^[2] Univ Sao Paulo, Fac Med, Dept Radiol, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF CLINICAL ULTRASOUND; v. 47, n. 8 JULY 2019.
• Citações Web of Science: 0

Resumo

Objective To evaluate perinodal fibrosis after 14-gauge staging core-needle biopsy (CNB) of the axillary sentinel lymph node (SLN) identified using contrast-enhanced ultrasonography (CEUS) and its interference with subsequent surgical SLN dissection in breast cancer patients. Methods Frequencies or means of main clinical, sonographic, pathological, and surgical characteristics were calculated. We also compared patient groups with and without perinodal pathological fibrosis. Results Forty-eight patients who underwent CEUS + CNB and axillary surgery were eligible for this cross-sectional study. Axillary surgical specimens showed perinodal fibrosis in 9/48 (18.7%) patients. Interference with SLN dissection was reported in 4/48 (8.3%) patients (two hematomas, three abnormal palpation findings, and four difficult dissections). The overall surgical detection rate of SLN was 43/48 (89.6%). In the majority of cases, perinodal fibrosis was described as moderate (4/9 {[}44.4%]) or severe (4/9 {[}44.4%]). The mean time elapsed between CEUS + CNB and axillary dissection was shorter in patients with perinodal fibrosis (P = .04). Interference with SLN dissection was only reported in patients with perinodal fibrosis (P < .001). Surgical SLN detection was successful in all nine cases in which perinodal pathological fibrosis or interference with SLN dissection was reported. Conclusion Perinodal fibrosis may impair the surgical SLN dissection in early stage breast cancer patients who were staged using CEUS + CNB using a14-gauge needle. (AU)

• Processo FAPESP: 15/22438-3 - Desempenho da biópsia percutânea de fragmento do linfonodo sentinela axilar detectado através do contraste ultrassonográfico na seleção dos casos com axila negativa ou com comprometimento axilar mínimo em mulheres com câncer de mama inicia
• Beneficiário: Gabrielle Baccarin
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica