Cardiovascular risk factors and major depressive disorder: a cross-sectional study in Sao Paulo, Brazil

Autor(es)

Bivanco-Lima, Danielle ^{[1, 2]} ; Santos, Itamar de Souza ^{[1, 3, 4]} ; Wang, Yuan-Pang ^{[1, 5]} ; Viana, Maria Carmen ^{[1, 6]} ; Andrade, Laura Helena ^{[1, 5]} ; Lotufo, Paulo Andrade ^{[1, 3, 4]} ; Bensenor, Isabela Judith Martins ^{[1, 3, 4]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sect Psychiat Epidemiol LIM 23, Inst Psychiat, Fac Med FMUSP, Sao Paulo, SP - Brazil

^[2] Fac Ciencias Med Santa Casa Sao Paulo FCMSP, Dept Publ Hlth, Sao Paulo, SP - Brazil

^[3] Univ Sao Paulo, Hosp Univ HU, Ctr Clin & Epidemiol Res, Sao Paulo, SP - Brazil

^[4] Univ Sao Paulo, Dept Internal Med, Fac Med FMUSP, Sao Paulo, SP - Brazil

^[5] Univ Sao Paulo, Sect Psychiat Epidemiol LIM 23, Inst Psychiat, Hosp Clin FMUSP, Fac Med, Sao Paulo, SP - Brazil

^[6] Univ Fed Espirito Santo UFES, Postgrad Program Collect Hlth, Vitoria, ES - Brazil

• Tipo de documento: Artigo Científico
• Fonte: São Paulo Medical Journal; v. 139, n. 4, p. 364-371, JUL-AUG 2021.
• Citações Web of Science: 0

Resumo

BACKGROUND: Cardiovascular risk factors can mediate the association between depression and cardiovascular diseases. OBJECTIVE: To evaluate cardiovascular risk factors in adult individuals with and without histories of major depression in the metropolitan region of Sao Paulo, Brazil. DESIGN AND SETTING: Cross-sectional study in Sao Paulo (SP), Brazil. METHODS: This study evaluated 423 individuals without any lifetime diagnosis of major depression and 203 individuals with a previous diagnosis of major depression (n = 626). The participants underwent a psychiatric evaluation using a structured clinical interview (SCID-1), an anthropometric evaluation and a clinical evaluation that included blood pressure measurement and assessment of fasting blood glucose, lipid profile and physical activity levels. RESULTS: Individuals with histories of major depression were more likely to be female (P < 0.0001). Individuals with lifetime diagnoses of major depression were more likely to be current smokers (odds ratio, OR 1.61; 95% confidence interval, CI 1.01-2.59) and to have diabetes (OR 1.79; 95% CI 1.01-3.21); and less likely to be obese (OR 0.58; 95% CI 0.35-0.94). CONCLUSION: Individuals with major depression had higher odds of presenting tobacco smoking and diabetes, and lower odds of being obese. Healthcare professionals need to be aware of this, so as to increase the rates of diagnosis and treatment in this population. (AU)

• Processo FAPESP: 03/00204-3 - Estudo epidemiológico dos transtornos psiquiátricos na região metropolitana de São Paulo: prevalências, fatores de risco e sobrecarga social e econômica
• Beneficiário: Laura Helena Silveira Guerra de Andrade
• Modalidade de apoio: Auxílio à Pesquisa - Temático