| Texto completo | |
| Autor(es): |
Martin, Francis L.
;
Morais, Camilo L. M.
;
Sakita, Juliana Yumi
;
Uyemura, Sergio Akira
;
Kannen, Vinicius
Número total de Autores: 5
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF GASTROINTESTINAL CANCER; v. 52, n. 1, p. 9-pg., 2020-04-04. |
| Resumo | |
Purpose Brazil is the largest country in South America. Although a developing nation, birth rates have been decreasing in the last few decades, while its overall population is undergoing lifestyle changes and ageing significantly. Moreover, Brazil has had increasingly high mortality rates related to colorectal cancer (CRC). Herein, we investigated whether the Brazilian population is exhibiting increasing mortality rates related to colon cancer (CC) or rectal cancer (RC) in recent years. Methods We examined data from the Brazilian Federal Government from 1979 to 2015 to determine whether CRC mortality and the population ageing process may be associated. Results Our mathematical modelling suggests that mortality rates related to CC and RC events in the Brazilian population may increase by 79% and 66% in the next 24 years, respectively. This finding led us to explore the mortality rates for both diseases in the country, and we observed that the highest levels were in the south and southeast regions from the year 2000 onwards. CC events appear to decrease life expectancy among people during their second decade of life in recent years, whereas RC events induced decreases in life expectancy in those aged >30 years. Additionally, both CC and RC events seem to promote significant mortality rates in the male population aged > 60 years and living in the southern states. Conclusion Our dataset suggests that both CC and RC events may lead to a significantly increasing number of deaths in the Brazilian male population in coming years. (AU) | |
| Processo FAPESP: | 14/06428-5 - Como a sinalização serotoninérgica epitelial difere dos efeitos de sua síntese neural durante a inflamação associada ou não ao câncer de cólon |
| Beneficiário: | Vinicius Kannen Cardoso |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |
| Processo FAPESP: | 15/01723-1 - Como a sinalização serotoninérgica epitelial difere dos efeitos de sua síntese neural durante a carcinogênese de cólon |
| Beneficiário: | Vinicius Kannen Cardoso |
| Modalidade de apoio: | Bolsas no Brasil - Jovens Pesquisadores |